CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-039304
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein Lama2 
Protein Synonyms/Alias
  
Gene Name
 Lama2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
224DLMMFAHKDPREIDPacetylation[1]
1234ETGFATYKPQVIIRGacetylation[1]
1715VAAEGLLKRVNKLFGacetylation[1]
1927TSPQGLLKEDAKGSLacetylation[1]
1936DAKGSLQKSFRILNEacetylation[1]
2034GLKQNYNKLADSVAKacetylation[1]
2047AKTNAVVKDPSKNSVacetylation[1]
2087KELEDNLKKNISEIKacetylation[1]
2122GDCIRTYKPEIKKGSacetylation[1]
2126RTYKPEIKKGSYNNIacetylation[1]
2349YLATRDLKDFMSVELacetylation[1]
2453ARPEVNVKKYSGCLKacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Disulfide bond; Laminin EGF-like domain; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 2546 AA 
Protein Sequence
GLFPAVLNLA SNALITTNAT CGEKGPEMYC KLVEHVPGQP VRNPQCRICN QNSSHPYQRH 60
PITNAIDGKN TWWQSPSIKN GVEYHYVTIT LDLQQVFQIA YVIVKAANSP RPGNWILERS 120
LDDEEYKPWQ YHAVTDTECL TLYNIYPRTG PPSYAKDDEV ICTSFYSKIH PLENGEIHIS 180
LINGRPSADD PSPELLEFTS ARYIRLRFQR IRTLNADLMM FAHKDPREID PIVTRRYYYS 240
VKDISVGGMC ICYGHARACP LDPATNKSRC ECEHNTCGES CDRCCPGFHQ KPWRAGTFLT 300
KTECEACNCH GKAEECYYDE TVASRNLSLN IHGKYIGGGV CINCTHNTAG INCETCIDGF 360
FRPKGVSPSY PRPCQPCHCD PAGSLSEVCI KDEKHTRRGL KPGSCYCKPG FGGMNCDRCV 420
RGYRGYPDCQ PCNCSGLGST NQDPCIGPCS CKENVEGEDC SHCKFGFFNL QEENQKGCEE 480
CFCSGVSDRC QSSYWTYGNI QDMHGWYLTD LSGRIQVAPQ LDNPDAPQQI SVSNSEARRS 540
LPDSYYWSAP APYLRNKLPA VGGQLSFTIS YDLEEEEDDT EKILQLMIIL EGNNLRISTA 600
YKEVHLEPSE EHVEELSLKE ESFTIHGTNL PVSRKDFMIL LTNLERVLIQ TTYNLGMDVI 660
FRLSSVNLES AVPYPTDRSI ASAVEVCQCP PGYSGSSCEA CWPRHRRVNG TIFGGLCEPC 720
QCFGHAEACN DVTGECLSCK DHTGGPYCNE CLPGFYGDPT RGTSEDCQPC ACPLNIPSNN 780
FSPTCHLDRS LGLICDECPV GYTGPRCERC AEGYFGQPSI PGGSCQPCLC NDNLDFSIPG 840
SCDSLSGSCL ICKPGTTGRF CELCADGYFG DAVDAKNCQP CRCNVNGSFS EICHRKTGQC 900
ECRPNVQGQR CDECKPETFG LQLGRGCIPC NCNSFGSKSF DCEASGQCWC QPGVAGKKCD 960
RCAHGYFNFQ EGGCTACDCS HLGNNCNPKT GQCICPPNTI GEKCSECLPN TWGHSIVTGC 1020
KVCNCSTVGS LSSQCNINTG QCSCHPKFSG MKCSECNRGH WNYPLCSLCD CFLPGTDATT 1080
CDSETRKCSC SDQTGQCTCK VNVEGVHCDR CRPGKFGLEA KNPLGCSSCY CFGVTSQCSE 1140
AKGLVRTWVT LRDEQTILPL VDEALQHTTT KGIAFQNPEI VAKMDEVRQD LHLEPFYWKL 1200
PEQFEGKKLM AYGGKLKYTI YFEARDETGF ATYKPQVIIR GGTPTHARII TRHMAAPLIG 1260
QLTRHEIEMT EKEWKYYGDD PRISRTVTRE DFLDILYDIH YILIKATYGN VVRQSRISEI 1320
SMEGAEPGQV SAASPLANLI ERCDCPPGYS GLSCETCAPG FYRVHSEPGG RTPGPTLGTC 1380
VPCQCHGHSS QCDPETSVCQ NCQHHTAGDF CERCALGYYG IVRGLPNDCQ PCACPLISPS 1440
NNFSPSCVLE GLEDYRCTAC PRGYEGQYCE RCAPGYAGSP SSPGGSCQEC ECDPYGSLPV 1500
PCDPVTGLCT CRPGATGRKC DGCEHGHARE GAECVFCGDE CTGLLLGDLA HLEQMAMNIN 1560
LTGPLPAPYK ILYGLENATQ ELKHLLSPQR APERLLQLAE GNMNTLVMEM NELLTRATKV 1620
TADGEQTGQD AERTNSRAQS LEEFIKGLVQ HAEAVNEKAI KLNETLGSQD RTAERNLQEL 1680
QKEIDRMLKE LRSKDLQTQK EVAEDELVAA EGLLKRVNKL FGEPRAQNEE MEKDLREKLA 1740
EYQNKLDDAW DLLREATKKT KDADRLSAAN QKNMTILETK KEAIEGSKRQ IENTLKEGND 1800
ILDEANRLAG EITSVIDYVE DIKTKLPPMS EELSDKIDDL AQEIKDRRLA EKVFQAESHA 1860
AQLNDSSAVL DGILDEAKNI SFNATAAFRA YSNIKDYIDE AEKVAREAKE LAHEATKLAT 1920
SPQGLLKEDA KGSLQKSFRI LNEAKKLAND VKENHNDLSG LKTRLETADL RNSGLLGALN 1980
DTMDKLSAIP NDTAAKLQAV KEKAREANDT AKAVLAQVKD LHQNLDGLKQ NYNKLADSVA 2040
KTNAVVKDPS KNSVVADAGA TVRNLEQEAD RLIDKLKPIK ELEDNLKKNI SEIKELINQA 2100
RKQANSIKVS VSSGGDCIRT YKPEIKKGSY NNIVVHVKTA VADNLLFYLG SAKFIDFLAI 2160
EMRKGKVSFL WDVGSGVGRV EYPDLTIDDS YWYRIEASRT GRNGSISVRA LDGPKASMVP 2220
STHHSVSPPG YTILDVDANA MLFVGGLTGK IKKADAVRVT TFTGCMGETY FDNKPIGLWN 2280
FREKEGDCKG CTVSPQVEDS EGTIQFDGEG YALVSRPIRW YPNISTVMFK FRTFSSNALL 2340
MYLATRDLKD FMSVELSDGH VKVSYDLGSG MASVVSNQNH NDGKWKSFTL SRIQKQANIS 2400
IVDIDSNQEE NIATSSSGNN FGLDLKADDK IYFGGLPTLR NLSMKARPEV NVKKYSGCLK 2460
DIEISRTPYN ILSSPNYVGV TKGCSLENVY TVSFPKPGFV ELAAVSIDVG TEINLSFSTR 2520
NESGIILLGS GGTLTPPRRK RRQTTQ 2546 
Gene Ontology
 GO:0005605; C:basal lamina; IDA:RGD.
 GO:0043197; C:dendritic spine; IDA:RGD.
 GO:0005606; C:laminin-1 complex; IEA:InterPro.
 GO:0007155; P:cell adhesion; IEA:InterPro.
 GO:0030198; P:extracellular matrix organization; IEP:RGD.
 GO:0022011; P:myelination in peripheral nervous system; IEP:RGD.
 GO:0030155; P:regulation of cell adhesion; IEA:InterPro.
 GO:0030334; P:regulation of cell migration; IEA:InterPro.
 GO:0045995; P:regulation of embryonic development; IEA:InterPro. 
Interpro
 IPR008985; ConA-like_lec_gl_sf.
 IPR013320; ConA-like_subgrp.
 IPR002049; EGF_laminin.
 IPR018031; Laminin_B_subgr.
 IPR000034; Laminin_B_type_IV.
 IPR001791; Laminin_G.
 IPR009254; Laminin_I.
 IPR010307; Laminin_II.
 IPR008211; Laminin_N. 
Pfam
 PF00052; Laminin_B
 PF00053; Laminin_EGF
 PF00054; Laminin_G_1
 PF06008; Laminin_I
 PF06009; Laminin_II
 PF00055; Laminin_N 
SMART
 SM00180; EGF_Lam
 SM00281; LamB
 SM00282; LamG
 SM00136; LamNT 
PROSITE
 PS01248; EGF_LAM_1
 PS50027; EGF_LAM_2
 PS50025; LAM_G_DOMAIN
 PS51115; LAMININ_IVA
 PS51117; LAMININ_NTER 
PRINTS