CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-015157
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Centrosomal protein of 85 kDa 
Protein Synonyms/Alias
 Coiled-coil domain-containing protein 21 
Gene Name
 CEP85 
Gene Synonyms/Alias
 CCDC21 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
139NGDLGAMKHSPGLSRubiquitination[1]
178ERQEEARKFDIPSMEubiquitination[1]
216NPRTSTSKELYRVLPubiquitination[1]
227RVLPEAKKAPGSGAVubiquitination[1]
260QPAPGLSKPLPSQVWubiquitination[1]
340NEHLLKEKELLIDKQubiquitination[1]
346EKELLIDKQRKHISQubiquitination[1]
349LLIDKQRKHISQLEQubiquitination[1]
357HISQLEQKVRESELQubiquitination[1, 2]
401LRAQFAQKTEALSREubiquitination[1, 2]
431QLIRESLKVALQKHSubiquitination[1]
530TQAICREKEIQLESLubiquitination[1]
574VEMESWQKRYDSLQKubiquitination[2]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 
Functional Description
  
Sequence Annotation
 MOD_RES 17 17 Phosphoserine.
 MOD_RES 623 623 Phosphoserine.  
Keyword
 Alternative splicing; Coiled coil; Complete proteome; Cytoplasm; Cytoskeleton; Nucleus; Phosphoprotein; Polymorphism; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 762 AA 
Protein Sequence
MAMQEKYPTE GISHVTSPSS DVIQKGSSLG TEWQTPVISE PFRSRFSRCS SVADSGDTAI 60
GTSCSDIAED FCSSSGSPPF QPIKSHVTIP TAHVMPSTLG TSPAKPNSTP VGPSSSKLPL 120
SGLAESVGMT RNGDLGAMKH SPGLSRDLMY FSGATGENGI EQSWFPAVGH ERQEEARKFD 180
IPSMESTLNQ SAMMETLYSD PHHRVRFHNP RTSTSKELYR VLPEAKKAPG SGAVFERNGP 240
HSNSSGVLPL GLQPAPGLSK PLPSQVWQPS PDTWHPREQS CELSTCRQQL ELIRLQMEQM 300
QLQNGAICHH PAAFGPSLPI LEPAQWISIL NSNEHLLKEK ELLIDKQRKH ISQLEQKVRE 360
SELQVHSALL GRPAPFGDVC LLRLQELQRE NTFLRAQFAQ KTEALSREKI DLEKKLSASE 420
VEVQLIRESL KVALQKHSEE VKKQEERVKG RDKHINNLKK KCQKESEQNR EKQQRIETLE 480
RYLADLPTLE DHQKQSQQLK DSELKSTELQ EKVTELESLL EETQAICREK EIQLESLRQR 540
EAEFSSAGHS LQDKQSVEET SGEGPEVEME SWQKRYDSLQ KIVEKQQQKM DQLRSQVQSL 600
EQEVAQEEGT SQALREEAQR RDSALQQLRT AVKELSVQNQ DLIEKNLTLQ EHLRQAQPGS 660
PPSPDTAQLA LELHQELASC LQDLQAVCSI VTQRAQGHDP NLSLLLGIHS AQHPETQLDL 720
QKPDVIKRKL EEVQQLRRDI EDLRTTMSDR YAQDMGENCV TQ 762 
Gene Ontology
 GO:0005813; C:centrosome; IDA:UniProtKB.
 GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
 GO:0005730; C:nucleolus; IDA:UniProtKB.
 GO:0000922; C:spindle pole; IDA:UniProtKB. 
Interpro
  
Pfam
  
SMART
  
PROSITE
  
PRINTS