| Tag | Content |
|---|
| CPLM ID | CPLM-008674 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Protein SDA1 |
Protein Synonyms/Alias | Severe depolymerization of actin protein 1 |
Gene Name | SDA1 |
Gene Synonyms/Alias | YGR245C |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 311 | KKLENAIKTVKKKKK | acetylation | [1] | | 521 | KKGGKDSKRPQFGAD | acetylation | [1] | | 696 | SREERLQKVLEGREG | acetylation | [1] |
|
Reference | [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae. Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C. Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [ PMID: 22865919] |
Functional Description | Required for 60S pre-ribosomal subunits export to the cytoplasm. May also be required for 60S ribosomal subunit maturation and accumulation. Involved in G1 events and passage through start, and possibly actin cytoskeleton organization. |
Sequence Annotation | MOD_RES 278 278 Phosphoserine. |
Keyword | Cell cycle; Complete proteome; Nucleus; Phosphoprotein; Protein transport; Reference proteome; Ribosome biogenesis; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 767 AA |
Protein Sequence | MGRRSRAAML PTNIILLQNL VKRDPESYQE EFLQQYAHYE SLRDIFMLNG LAGGDSAAAT 60
NGLDVGNGSS TMAGTNGTTM STSTSQLIEL VGFVSQVCSC FPRETANFPS ELKQLLLEHH 120
KSLPFELKEK ILSCLTMLRN KDVITAEELI QSLFPLLVAY SSHGNSLGVN SHAKELRKII 180
YTNLISLLKS CNTNGKNQKL NKSTQAVCFN LLDQPDSQGI WATKLTRELW RRGIWDDSRT 240
VEIMTQAALH QDVKIVMSGV MFFLDADRER EENFEENSED EDGFDLDALR HKMQVNKKTG 300
RRGKKLENAI KTVKKKKKNG PGAPQGYLNF SAIHLLRDPQ GFAEKLFKEH LSGKTKNKFD 360
MEQKISLMQL LSRLIGTHKL IVLGIYTFFL KYLTPKQRDV TRIMSACAQA CHDLVPPEVI 420
NVMVRKIADE FVSDGVANEV AAAGINTIRE ICSRAPLAID EILLQDLVEY KGSKAKGVNM 480
AAKSLIALYR DVAPEMLKKK DRGKNAAMEV QEAKKGGKDS KRPQFGADNS VQGIAGIELL 540
AKWKKEHGEE SENEDADANW EVDVDSEEDD VDGEWVTMDS DKEYDVDMED SDDEKDNAKG 600
KESDSDLELS DDDDEKEVKD EQEDADIDPE AAFREIASTR ILTPADFAKL QELRNEESVA 660
KIMGIHKQDK REELVDASTL TGPIKYKQSR EERLQKVLEG REGRDKFGSR RGKRDNMRST 720
TNREKERRKN FVMSIHKRSV RGKQKMSLRD KQKVLRAHIT KQKKKGY 767 |
Gene Ontology | GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell. GO:0005634; C:nucleus; IDA:SGD. GO:0030036; P:actin cytoskeleton organization; IMP:SGD. GO:0007049; P:cell cycle; IEA:UniProtKB-KW. GO:0015031; P:protein transport; IEA:UniProtKB-KW. GO:0042273; P:ribosomal large subunit biogenesis; IMP:SGD. GO:0000055; P:ribosomal large subunit export from nucleus; IMP:SGD. GO:0007089; P:traversing start control point of mitotic cell cycle; IMP:SGD. |
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SMART | |
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