| Tag | Content |
|---|
| CPLM ID | CPLM-001660 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Protein Wiz |
Protein Synonyms/Alias | Widely-interspaced zinc finger-containing protein; Zinc finger protein 803 |
Gene Name | WIZ |
Gene Synonyms/Alias | ZNF803 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 740 | VGNIYTLKCRFCEVE | ubiquitination | [1] | | 773 | ILEMNFSKADPPPEE | ubiquitination | [1] |
|
Reference | [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization. Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW. Nature. 2013 Apr 18;496(7445):372-6. [ PMID: 23503661] |
Functional Description | May link EHMT1 and EHMT2 histone methyltransferases to the CTBP corepressor machinery. May be involved in EHMT1-EHMT2 heterodimer formation and stabilization (By similarity). |
Sequence Annotation | ZN_FING 267 289 C2H2-type 1.
ZN_FING 304 326 C2H2-type 2.
ZN_FING 353 375 C2H2-type 3.
ZN_FING 416 439 C2H2-type 4.
ZN_FING 701 723 C2H2-type 5.
ZN_FING 769 791 C2H2-type 6.
ZN_FING 870 892 C2H2-type 7.
ZN_FING 1043 1065 C2H2-type 8.
ZN_FING 1227 1249 C2H2-type 9.
ZN_FING 1397 1419 C2H2-type 10.
ZN_FING 1596 1622 C2H2-type 11.
REGION 1030 1034 Interaction with CTBP1 and CTBP2 1 (By
REGION 1214 1218 Interaction with CTBP1 and CTBP2 2 (By
MOD_RES 996 996 Phosphoserine.
MOD_RES 998 998 Phosphothreonine.
MOD_RES 1006 1006 Phosphoserine.
MOD_RES 1012 1012 Phosphoserine.
MOD_RES 1017 1017 Phosphoserine.
MOD_RES 1079 1079 Phosphoserine.
MOD_RES 1127 1127 Phosphoserine.
MOD_RES 1134 1134 Phosphoserine.
MOD_RES 1146 1146 Phosphoserine.
MOD_RES 1151 1151 Phosphoserine.
MOD_RES 1162 1162 N6,N6,N6-trimethyllysine; by EHMT2;
MOD_RES 1162 1162 N6,N6-dimethyllysine; by EHMT2;
MOD_RES 1263 1263 Phosphoserine.
MOD_RES 1309 1309 Phosphoserine.
MOD_RES 1314 1314 Phosphoserine.
MOD_RES 1517 1517 Phosphoserine. |
Keyword | Alternative splicing; Complete proteome; Metal-binding; Methylation; Nucleus; Phosphoprotein; Reference proteome; Repeat; Zinc; Zinc-finger. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 1651 AA |
Protein Sequence | MEGSLAGSLA APDRPQGPER LPGPAPRENI EGGAEAAEGE GGIFRSTRYL PVTKEGPRDI 60
LDGRGGISVA NFDPGTFSLM RCDFCGAGFD TRAGLSSHAR AHLRDFGITN WELTVSPINI 120
LQELLATSAA EQPPSPLGRE PGGPPGSFLT SRRPRLPLTV PFPPTWAEDP GPAYGDASGP 180
EPARDIRCEF CGEFFENRKG LSSHARSHLR QMGVTEWYVN GSPIDTLREI LKRRTQSRPG 240
GPPNPPGPSP KALAKMMGGA GPGSSLEARS PSDLHISPLA KKLPPPPGSP LGHSPTASPP 300
PTARKMFPGL AAPSLPKKLK PEQIRVEIKR EMLPGALHGE LHPSEGPWGA PREDMTPLNL 360
SSRAEPVRDI RCEFCGEFFE NRKGLSSHAR SHLRQMGVTE WSVNGSPIDT LREILKKKSK 420
PCLIKKEPPA GDLAPALAED GPPTVAPGPV QSPLPLSPLA GRPGKPGAGP AQVPRELSLT 480
PITGAKPSAT GYLGSVAAKR PLQEDRLLPA EVKAKTYIQT ELPFKAKTLH EKTSHSSTEA 540
CCELCGLYFE NRKALASHAR AHLRQFGVTE WCVNGSPIET LSEWIKHRPQ KVGAYRSYIQ 600
GGRPFTKKFR SAGHGRDSDK RPSLGLAPGG LAVVGRSAGG EPGPEAGRAA DGGERPLAAS 660
PPGTVKAEEH QRQNINKFER RQARPPDASA ARGGEDTNDL QQKLEEVRQP PPRVRPVPSL 720
VPRPPQTSLV KFVGNIYTLK CRFCEVEFQG PLSIQEEWVR HLQRHILEMN FSKADPPPEE 780
SQAPQAQTAA AEAP 794 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |