| Tag | Content |
|---|
| CPLM ID | CPLM-019495 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Zinc finger protein 599 |
Protein Synonyms/Alias | |
Gene Name | ZNF599 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 253 | MRLHTGEKPYKCIEC | ubiquitination | [1] |
|
Reference | [1] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C. Nat Cell Biol. 2012 Oct;14(10):1089-98. [ PMID: 23000965] |
Functional Description | May be involved in transcriptional regulation. |
Sequence Annotation | DOMAIN 9 80 KRAB.
ZN_FING 199 221 C2H2-type 1.
ZN_FING 227 249 C2H2-type 2.
ZN_FING 255 277 C2H2-type 3.
ZN_FING 283 305 C2H2-type 4.
ZN_FING 311 333 C2H2-type 5.
ZN_FING 339 361 C2H2-type 6.
ZN_FING 367 389 C2H2-type 7.
ZN_FING 395 417 C2H2-type 8.
ZN_FING 423 445 C2H2-type 9.
ZN_FING 451 473 C2H2-type 10.
ZN_FING 479 501 C2H2-type 11.
ZN_FING 507 529 C2H2-type 12.
ZN_FING 535 557 C2H2-type 13.
ZN_FING 563 585 C2H2-type 14. |
Keyword | Alternative splicing; Complete proteome; DNA-binding; Metal-binding; Nucleus; Polymorphism; Reference proteome; Repeat; Transcription; Transcription regulation; Zinc; Zinc-finger. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 588 AA |
Protein Sequence | MAAPALALVS FEDVVVTFTG EEWGHLDLAQ RTLYQEVMLE TCRLLVSLGH PVPKPELIYL 60
LEHGQELWTV KRGLSQSTCA GEKAKPKITE PTASQLAFSE ESSFQELLAQ RSSRDSRLGQ 120
ARDEEKLIKI QEGNLRPGTN PHKEICPEKL SYKHDDLEPD DSLGLRVLQE RVTPQDALHE 180
CDSQGPGKDP MTDARNNPYT CTECGKGFSK KWALVRHQQI HAGVKPYECN ECGKACRYMA 240
DVIRHMRLHT GEKPYKCIEC GKAFKRRFHL TEHQRIHTGD KPYECKECGK AFTHRSSFIQ 300
HNMTHTREKP FLCKECGKAF YYSSSFAQHM RIHTGKKLYE CGECGKAFTH RSTFIQHNVT 360
HTGEKPFLCK ECGKTFCLNS SFTQHMRIHT GEKPYECGEC GKAFTHRSTF IRHKRTHTGE 420
KPFECKECGK AFCDSSSLIQ HMRIHTGEKP YECSECGKAF THHSVFIRHN RTHSGQKPLE 480
CKECAKAFYY SSSFTRHMRI HTGEKPYVCR ECGKAFTQPA NFVRHNRIHT GEKPFECKEC 540
EKAFCDNFAL TQHMRTHTGE KPFECNECGK TFSHSSSFTH HRKIHTRV 588 |
Gene Ontology | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. GO:0003677; F:DNA binding; IEA:UniProtKB-KW. GO:0008270; F:zinc ion binding; IEA:InterPro. GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW. GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |