Tag | Content |
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CPLM ID | CPLM-020039 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Kelch domain-containing protein 3 |
Protein Synonyms/Alias | Protein Peas; Testis intracellular mediator protein |
Gene Name | KLHDC3 |
Gene Synonyms/Alias | PEAS |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
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63 | WTKLPPVKSAIRGQA | ubiquitination | [1] | 114 | AFDVNTHKWFTPRVS | ubiquitination | [1] |
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Reference | [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments. Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA. Mol Cell Proteomics. 2013 Mar;12(3):825-31. [ PMID: 23266961] |
Functional Description | May be involved in meiotic recombination process. |
Sequence Annotation | REPEAT 25 77 Kelch 1. REPEAT 88 138 Kelch 2. REPEAT 139 189 Kelch 3. REPEAT 191 249 Kelch 4. REPEAT 251 301 Kelch 5. |
Keyword | Complete proteome; Cytoplasm; Kelch repeat; Meiosis; Reference proteome; Repeat. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 382 AA |
Protein Sequence | MLRWTVHLEG GPRRVNHAAV AVGHRVYSFG GYCSGEDYET LRQIDVHIFN AVSLRWTKLP 60 PVKSAIRGQA PVVPYMRYGH STVLIDDTVL LWGGRNDTEG ACNVLYAFDV NTHKWFTPRV 120 SGTVPGARDG HSACVLGKIM YIFGGYEQQA DCFSNDIHKL DTSTMTWTLI CTKGSPARWR 180 DFHSATMLGS HMYVFGGRAD RFGPFHSNNE IYCNRIRVFD TRTEAWLDCP PTPVLPEGRR 240 SHSAFGYNGE LYIFGGYNAR LNRHFHDLWK FNPVSFTWKK IEPKGKGPCP RRRQCCCIVG 300 DKIVLFGGTS PSPEEGLGDE FDLIDHSDLH ILDFSPSLKT LCKLAVIQYN LDQSCLPHDI 360 RWELNAMTTN SNISRPIVSS HG 382 |
Gene Ontology | GO:0005829; C:cytosol; TAS:Reactome. GO:0000790; C:nuclear chromatin; IDA:UniProtKB. GO:0003682; F:chromatin binding; IDA:UniProtKB. GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome. GO:0044267; P:cellular protein metabolic process; TAS:Reactome. GO:0007131; P:reciprocal meiotic recombination; NAS:UniProtKB. |
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