CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-010354
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Uncharacterized oxidoreductase YajO 
Protein Synonyms/Alias
  
Gene Name
 yajO 
Gene Synonyms/Alias
 b0419; JW0409 
Created Date
 July 27, 2013 
Organism
 Escherichia coli (strain K12) 
NCBI Taxa ID
 83333 
Lysine Modification
Position
Peptide
Type
References
45ESSRPIIKRALEGGIacetylation[1]
88EDVVVATKVFHRVGDacetylation[1]
237LVSDEVGKNLYKESDacetylation[1]
241EVGKNLYKESDENDAacetylation[1]
Reference
 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618
Functional Description
  
Sequence Annotation
 NP_BIND 212 222 NADP (By similarity).
 ACT_SITE 61 61 Proton donor (By similarity).  
Keyword
 Complete proteome; NADP; Oxidoreductase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 324 AA 
Protein Sequence
MQYNPLGKTD LRVSRLCLGC MTFGEPDRGN HAWTLPEESS RPIIKRALEG GINFFDTANS 60
YSDGSSEEIV GRALRDFARR EDVVVATKVF HRVGDLPEGL SRAQILRSID DSLRRLGMDY 120
VDILQIHRWD YNTPIEETLE ALNDVVKAGK ARYIGASSMH ASQFAQALEL QKQHGWAQFV 180
SMQDHYNLIY REEEREMLPL CYQEGVAVIP WSPLARGRLT RPWGETTARL VSDEVGKNLY 240
KESDENDAQI AERLTGVSEE LGATRAQVAL AWLLSKPGIA APIIGTSREE QLDELLNAVD 300
ITLKPEQIAE LETPYKPHPV VGFK 324 
Gene Ontology
 GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
 GO:0006772; P:thiamine metabolic process; EXP:EcoliWiki. 
Interpro
 IPR001395; Aldo/ket_red.
 IPR020471; Aldo/keto_reductase_subgr.
 IPR023210; NADP_OxRdtase_dom. 
Pfam
 PF00248; Aldo_ket_red 
SMART
  
PROSITE
  
PRINTS
 PR00069; ALDKETRDTASE.