CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-043865
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Putative deoxyribonuclease TATDN2 
Protein Synonyms/Alias
  
Gene Name
 TATDN2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
154GEAATRAKPSAAEHPubiquitination[1]
460SFQGTFTKFRKIYSSubiquitination[1]
471IYSSSFPKEFQGCISubiquitination[1, 2]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 665 AA 
Protein Sequence
QKEDDVACSR RLSWGSSRRR NNSSSSFSPH FLGPGVGGAA SKGCLIRNTR GFLSSGGSPL 60
RPANASLEEM ASLEEEACSL KVDSKDSSHN STNSEFAAEA EGQNDTIEEP NKVQKRKRDR 120
LRDQGSTMIY LKAIQGILGK SMPKRKGEAA TRAKPSAAEH PSHGEGPARS EGPAKTAEGA 180
ARSVTVTAAQ KEKDATPEVS MEEDKTVPER SSFYDRRVVI DPQEKPSEEP LGDRRTVIDK 240
CSPPLEFLDD SDSHLEIQKH KDREVVMEHP SSGSDWSDVE EISTVRFSQE EPVSLKPSAV 300
PEPSSFTTDY VMYPPHLYSS PWCDYASYWT SSPKPSSYPS TGSSSNDAAQ VGKSSRSRMS 360
DYSPNSTGSV QNTSRDMEAS EEGWSQNSRS FRFSRSSEER EVKEKRTFQE EMPPRPCGGH 420
ASSSLPKSHL EPSLEEGFID THCHLDMLYS KLSFQGTFTK FRKIYSSSFP KEFQGCISDF 480
CDPRTLTDCL WEELLKEDLV WGAFGCHPHF ARYYSESQER NLLQALRHPK AVAFGEMGLD 540
YSYKCTTPVP EQHKVFERQL QLAVSLKKPL VIHCREADED LLEIMKKFVP PDYKIHRHCF 600
TGSYPVIEPL LKYFPNMSVG FTAVLTYSSA WEAREALRQI PLERIIVETD APYFLPRQAV 660
QSPTL 665 
Gene Ontology
 GO:0016888; F:endodeoxyribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro. 
Interpro
 IPR018228; DNase_TatD-rel_CS.
 IPR001130; TatD_family. 
Pfam
 PF01026; TatD_DNase 
SMART
  
PROSITE
 PS01137; TATD_1
 PS01090; TATD_2
 PS01091; TATD_3 
PRINTS