CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-035225
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Eukaryotic translation initiation factor 2 subunit 1 
Protein Synonyms/Alias
 Eukaryotic translation initiation factor 2A, isoform CRA_a 
Gene Name
 Eif2a 
Gene Synonyms/Alias
 rCG_50019 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
86CLKSFIQKKMQNWCPacetylation[1]
124NFNTIANKLHLQKVNacetylation[1]
143SPGTQPFKVAVYVPGacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Initiation factor; Protein biosynthesis; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 541 AA 
Protein Sequence
MDPHTSQRAQ CFQENLEKIA KSILLVRMGH CLPGAMEKIC LEFSPNNTVL ATWQPYTTSK 60
DGTAGTPNLQ LYDVKTGTCL KSFIQKKMQN WCPSWSDDEI ICARNVNNEV HFFENNNFNT 120
IANKLHLQKV NDFNLSPGTQ PFKVAVYVPG SKGAPSFVRL YQYPNFAGPQ AALANKSFFK 180
ADKVTMLWNK KATAVLVIAS TDVDKTGASY YGEQTLHYIA TNGESAVVQL PKNGPIYDVA 240
WNPSSTEFCA VYGFMPAKAT VFNLKCDPVF DFGTGPRNAA FYSPHGHILV LAGFGNLRGQ 300
MEVWDVKNYK LISKPVASDS TYFAWCPDGE HILTATCAPR LRVNNGYKIW HYTGSLLYKY 360
DVPSNGELWQ VSWQPFLDGI FPAKTITYQA VPSEVPSEEP KVATAYRPPA LRNKPVTSSK 420
LHEEEPPQNM KPHPSSDKPL SKTALKNQRK HEAKKAAKQE ARNDLAPTPV PQSAPRSTVT 480
QSASGDPEVD KKIKNLKKKL KAIEQLKEQA AAGKQLEKNQ LEKIQKETAL LQELEDLELG 540
V 541 
Gene Ontology
 GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW. 
Interpro
 IPR011387; TIF2A.
 IPR013979; TIF_beta_prop-like.
 IPR015943; WD40/YVTN_repeat-like_dom. 
Pfam
 PF08662; eIF2A 
SMART
  
PROSITE
  
PRINTS