CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-011512
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Nucleolar protein 6 
Protein Synonyms/Alias
  
Gene Name
 NOP6 
Gene Synonyms/Alias
 YDL213C; D1018 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
184ERKERLTKMINDGNQacetylation[1]
Reference
 [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919
Functional Description
 Predicted to be involved in rRNA processing. 
Sequence Annotation
 DOMAIN 78 155 RRM.
 MOD_RES 45 45 Phosphoserine.
 MOD_RES 160 160 Phosphoserine.  
Keyword
 Complete proteome; Nucleus; Phosphoprotein; Reference proteome; Ribosome biogenesis; RNA-binding; rRNA processing. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 225 AA 
Protein Sequence
MGSEEDKKLT KKQLKAQQFR KSKEEKDQEK DVKKEQAPEG KRPNSAAGND GEEPVKKKRK 60
TRRGRGGKGK NGKKGNRFIV FVGSLPRDIT AVELQNHFKN SSPDQIRLRA DKGIAFLEFD 120
ADKDRTGIQR RMDIALLQHG TLLKEKKINV ELTVGGGGNS QERLEKLKNK NIKLDEERKE 180
RLTKMINDGN QKKIAKTTAT AAQTSGTDNK PVPAGIHPDR AKLLK 225 
Gene Ontology
 GO:0030686; C:90S preribosome; IDA:SGD.
 GO:0005730; C:nucleolus; IDA:SGD.
 GO:0000166; F:nucleotide binding; IEA:InterPro.
 GO:0019843; F:rRNA binding; IDA:SGD.
 GO:0030515; F:snoRNA binding; IDA:SGD.
 GO:0042274; P:ribosomal small subunit biogenesis; IGI:SGD.
 GO:0006364; P:rRNA processing; IEA:UniProtKB-KW. 
Interpro
 IPR012677; Nucleotide-bd_a/b_plait.
 IPR000504; RRM_dom. 
Pfam
  
SMART
 SM00360; RRM 
PROSITE
 PS50102; RRM 
PRINTS