CPLM 1.0 - Compendium of Protein Lysine Modification
Tag
Content
CPLM ID
CPLM-038578
UniProt Accession
E9Q876_MOUSE
;
E9Q876
Genbank Protein ID
AC107789
;
AC138589
Genbank Nucleotide ID
Protein Name
Protein Abca12
Protein Synonyms/Alias
Gene Name
Abca12
Gene Synonyms/Alias
Created Date
July 27, 2013
Organism
Mus musculus (Mouse)
NCBI Taxa ID
10090
Lysine Modification
Position
Peptide
Type
References
1735
KIMAILI
K
RFHHTRR
acetylation
[1]
1735
KIMAILI
K
RFHHTRR
succinylation
[1]
Reference
[1] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
Mol Cell. 2013 Jun 27;50(6):919-30. [
PMID: 23806337
]
Functional Description
Sequence Annotation
Keyword
ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.
Sequence Source
UniProt (SWISSPROT/TrEMBL); GenBank; EMBL
Protein Length
2595 AA
Protein Sequence
MASQFHQLRI LVWKNWLGVK RQPLWTLVLI LWPVIIFIIL AITRTKFPPT AKPTCYLAPR 60
NLPSAGFFPF LQTLLCDTDS KCKDTPYGPR DLLRRKGIDG PLFKESEILK KPSNPKRDSN 120
LSLRSTQVPE RSHTSLATVP PRPSYDLEGT GTENFNGSQL LTRILGLEKL LKQNSTPEDI 180
RRELCESYPG YTADYAFSWV TLGKNVFNKF CLSNMTLLES SLQELKYQVS QMSSDPDNQK 240
RVFRGLVQVL SFFSQVQQQR EVWQLLSSLP DVFQNGTSLS SLFGVLQKAN RVLLVVQKVY 300
PRVQTDEGFS TLQKSVKHLL NTLDSPMQGD NSTHAWSDDD EQTLSPSSLA AQLLILENFE 360
DAILNISSNS PYSPYLACVR NMTDNLAKGS PDNLKLLQST IHFRKSFLQN GSSEDSFPPF 420
LEILKSKLSQ LRNLTELLCE SETFSSIKKS CQFSNMSFER LCEDHAFHVQ LIEAAELGTD 480
LTTGLLYHDN IISAKLRGLL TGDPSKINLN VDWLLEQALQ MNYLENITRL IPTVEAMLHV 540
NTSADASEKP GQLREMFKNI DLLKEDLRAI GMSNTSIDKL LAIPIPDNRA EIISRVFWLH 600
SCDTNVTNPK LEDAMKEFCK LPLPERSHQS YLIGLTLLHY LDIYNFTYKV FFPRKDQKPM 660
ERMMELFIKL REILNQLASG THPLLDKMRS LRQMHLPRSV PLTQAMYRNT RMNSPAGSFS 720
TISQALCSQG ITTEYLTAML PSSQKPKGNH TKDFLTYKLT KEEIASKYGI PLNATPFCFS 780
LYKDIINMPA GPVIWAFLKP MLLGKILYSP YNPTTKAIME KSNVTLRQLA ELREKSQEWM 840
DKSPIFMNSF HLLNQTIPML QNTLRNPFVQ VFVKFSVGLD AVELLKQIDD LDVLRLKLVN 900
NIDIIDQLNT LSSLTVNISS CVLYDRIQAS DTVEEMETVA EQLYKSNELF GSVIFKLPSN 960
GSLHRGFDPE KVSLPPIVRY TIRMSLKTAQ TTRSIRTKIW APGPHNSPSH NQIYGRAFIY 1020
LQDSIERAII ELQTGRNSQE VAVQVQAVPY PCFMKDNFLT SVSYSLPIVL MVAWVVFIAA 1080
FVKKLVYEKD LRLHEYMKMM GVNSCSHFFA WLIESIGFLL VTIAILIVIL KFGNILPKTN 1140
GFILFLYFSD YSFSVIAMSY LISVFFNNTN IAALIGSLIY VIAFFPFIVL VTVEDELSYV 1200
IKVFMSLLSP TAFSYASQYI ARYEEQGVGL QWENMYKSPV QDDTTSFGWL CCLILADSFI 1260
YFFIAWYVRN VFPGTYGMAA PWYFPILPSY WKERFGCAEV KHEKSNGLMF TNIMMQNTNP 1320
SASKTSPDCA FPSNIEPEPK DLQVGVALHG VTKIYGSKTA VENLNLNFYE GHITSLLGPN 1380
GAGKTTTISM LTGLFGATAG TIFVYGKDIK TDLNTVRKNM GVCMQHDVLF SYLTTKEHLL 1440
LYGSIKVPHW TKTQLHEEVK RTLKDTGLYS HRHKRVGTLS GGMKRKLSIS IALIGGSRVV 1500
ILDEPSTGVD PCSRRSIWDV ISKNKTARTI ILSTHHLDEA EVLSDRIAFL EQGGLRCCGS 1560
PFYLKEAFGD GYHLTLTKKK SPNLDTNAIC DTVAVTAMIQ SHLPEAYLKE DIGGELVYVL 1620
PPFSTKVSGA YLSLLRALDK GMGKLNIGCY GISDTTVEEV FLNLTKDSQK SSNMSLEHLT 1680
QRKVGNPSAN GTSTPDDLSV SSSNFTDRDD KVLTRSEKLE GFGLLLKKIM AILIKRFHHT 1740
RRNWKGLIAQ VILPIVFVAT AMGLGTLRDS SNSYPEIMIS PSIYGTSEQT AFYANFDPST 1800
SGLVSALWNF PGIDNVCLNT SDLQCLKKDD LGKWNTSGEA IDNFGVCSCS DNVQECPKFN 1860
YHPPHRRTYS SQVIYNLTGK HMENYLITTA NHFVQKRYGG WSFGMKLTND LRFDVTAVPD 1920
NRTLAKVWYD PEGYHSLPAY LNSLNNFLLR VNMSEYDAAR HGIIMYSHPY PGVQDQEQAT 1980
ISSLIDILVA LSILMGYSVT TASFVTYIVR EHQTKAKQLQ HISGIGVTCY WVTNFIYDMV 2040
FYLVPVAFSI GVIAIFKLPA FYSGNNLGAV SLLLLLFGYA TFSWMYLLAG LFHETGMAFI 2100
TYVCVNLFFG INSIVSLSVV YFLSKEKPND PTLELISETL KRIFLIFPQF CFGYGLIELS 2160
QQQAVLDFLK AYGVEYPSET FEMDKLGAMF VALVSQGTMF FLLRLLINEW LIKKLRLFFR 2220
KFTSSPIMET VDEDEDVRAE RFRVESGAAE FDLVQLHRLT KTYQLIHKKI IAVNNISLGI 2280
PAGECFGLLG VNGAGKTTIF KMLTGDIIPS SGNILIRNKS GSLGHVDSHS SLVGYCPQED 2340
ALDDLVTVEE HLYFYARVHG IPEKDIKDTV HKLLRRLHLM AYKDRSTSMC SYGTKRKLST 2400
ALALIGKPSI LLLDEPSSGM DPKSKRHLWR IISEEVQNKC SVILTSHSME ECEALCTRLA 2460
IMVNGRFQCI GSLQHIKSRF GRGFTVKVHL KNNKVSMETL TKFMQLHFPK TYLKDQHLSM 2520
LEYHVPVTAG GVANIFDLLE TNKTALNITN FLVSQTTLEE VFINFAKDQK SYENVDTSSQ 2580
GSTISVDSQE DQLDS 2595
Gene Ontology
GO:0005829
; C:cytosol; IDA:MGI.
GO:0005743
; C:mitochondrial inner membrane; IDA:MGI.
GO:0005524
; F:ATP binding; IEA:UniProtKB-KW.
GO:0016887
; F:ATPase activity; IEA:InterPro.
GO:0006200
; P:ATP catabolic process; IEA:GOC.
GO:0035627
; P:ceramide transport; IMP:MGI.
GO:0061436
; P:establishment of skin barrier; IMP:MGI.
GO:0031424
; P:keratinization; IMP:MGI.
GO:0055088
; P:lipid homeostasis; IMP:MGI.
GO:0048286
; P:lung alveolus development; IMP:MGI.
GO:0043129
; P:surfactant homeostasis; IMP:MGI.
Interpro
IPR003593
; AAA+_ATPase.
IPR026082
; ABC_A.
IPR003439
; ABC_transporter-like.
IPR017871
; ABC_transporter_CS.
IPR027417
; P-loop_NTPase.
Pfam
PF00005
; ABC_tran
SMART
SM00382
; AAA
PROSITE
PS00211
; ABC_TRANSPORTER_1
PS50893
; ABC_TRANSPORTER_2
PRINTS