CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-032887
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Exportin-1 
Protein Synonyms/Alias
  
Gene Name
 XPO1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
54QEVLTHLKEHPDAWTubiquitination[1, 2, 3]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 62 AA 
Protein Sequence
MPAIMTMLAD HAARQLLDFS QKLDINLLDN VVNCLYHGEG AQQRMAQEVL THLKEHPDAW 60
TR 62 
Gene Ontology
 GO:0005634; C:nucleus; IEA:Compara.
 GO:0008565; F:protein transporter activity; IEA:Compara.
 GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Compara.
 GO:0006611; P:protein export from nucleus; IEA:Compara.
 GO:0034504; P:protein localization to nucleus; IEA:Compara.
 GO:0010824; P:regulation of centrosome duplication; IEA:Compara.
 GO:0042176; P:regulation of protein catabolic process; IEA:Compara.
 GO:0046825; P:regulation of protein export from nucleus; IEA:Compara.
 GO:0042493; P:response to drug; IEA:Compara. 
Interpro
  
Pfam
  
SMART
  
PROSITE
  
PRINTS