UniProt Accession

 YBIS_ECOLI; P0AAX8; P75789 

Genbank Protein ID

 U00096; AP009048 

Genbank Nucleotide ID

 AAC73906.1; BAA35500.1 

Protein Name

 Probable L,D-transpeptidase YbiS 

Protein Synonyms/Alias

  

Gene Name

 ybiS 

Gene Synonyms/Alias

 b0819; JW0803 

Created Date

 July 27, 2013 

Organism

 Escherichia coli (strain K12) 

NCBI Taxa ID

 83333 

Lysine Modification

Position	Peptide	Type	References
115	MRLYYYPKGTNTVIV	acetylation	[1]
132	IGIGQLGKDTPINWT	acetylation	[1]
141	TPINWTTKVERKKAG	acetylation	[1]
219	RLRNEDIKFLFEKVP	acetylation	[1]
224	DIKFLFEKVPVGTRV	acetylation	[1]

Reference

 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 

Functional Description

 Responsible, at least in part, for anchoring of the major outer membrane lipoprotein (Lpp, also known as the Braun lipoprotein) to the peptidoglycan via a meso-diaminopimelyl-L-Lys- bond on the terminal residue of Lpp. Can be oxidized in vivo, its reduction depends preferentially on DsbG, although DsbC is able to partially replace DsbG. 

Sequence Annotation

 ACT_SITE 210 210 Potential.  

Keyword

 Cell shape; Cell wall biogenesis/degradation; Complete proteome; Direct protein sequencing; Glycosyltransferase; Hydrolase; Peptidoglycan synthesis; Periplasm; Reference proteome; Signal; Transferase. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 306 AA 

Protein Sequence

Gene Ontology

 GO:0042597; C:periplasmic space; IDA:EcoCyc.
 GO:0016807; F:cysteine-type carboxypeptidase activity; IMP:EcoCyc.
 GO:0071972; F:peptidoglycan L,D-transpeptidase activity; IMP:EcoCyc.
 GO:0016755; F:transferase activity, transferring amino-acyl groups; IMP:EcoCyc.
 GO:0016757; F:transferase activity, transferring glycosyl groups; IEA:UniProtKB-KW.
 GO:0043164; P:Gram-negative-bacterium-type cell wall biogenesis; IMP:EcoCyc.
 GO:0018104; P:peptidoglycan-protein cross-linking; IMP:EcoCyc.
 GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW. 

Interpro

 IPR005490; LD_TPept_cat_dom. 

Pfam

 PF03734; YkuD 

SMART

  

PROSITE

  

PRINTS