CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-022427
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Stathmin-3 
Protein Synonyms/Alias
 SCG10-like protein 
Gene Name
 STMN3 
Gene Synonyms/Alias
 SCLIP 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
59QSFEVILKSPSDLSPubiquitination[1]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983
Functional Description
 Exhibits microtubule-destabilizing activity, which is antagonized by STAT3 (By similarity). 
Sequence Annotation
 DOMAIN 38 180 SLD.
 MOD_RES 65 65 Phosphoserine (By similarity).
 MOD_RES 68 68 Phosphoserine (By similarity).
 MOD_RES 73 73 Phosphoserine (By similarity).
 LIPID 22 22 S-palmitoyl cysteine (By similarity).
 LIPID 24 24 S-palmitoyl cysteine (By similarity).  
Keyword
 Cell projection; Coiled coil; Complete proteome; Golgi apparatus; Lipoprotein; Palmitate; Phosphoprotein; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 180 AA 
Protein Sequence
MASTISAYKE KMKELSVLSL ICSCFYTQPH PNTVYQYGDM EVKQLDKRAS GQSFEVILKS 60
PSDLSPESPM LSSPPKKKDT SLEELQKRLE AAEERRKTQE AQVLKQLAER REHEREVLHK 120
ALEENNNFSR QAEEKLNYKM ELSKEIREAH LAALRERLRE KELHAAEVRR NKEQREEMSG 180 
Gene Ontology
 GO:0030424; C:axon; IEA:UniProtKB-SubCell.
 GO:0005737; C:cytoplasm; ISS:HGNC.
 GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
 GO:0030426; C:growth cone; IEA:UniProtKB-SubCell.
 GO:0019904; F:protein domain specific binding; ISS:HGNC.
 GO:0031122; P:cytoplasmic microtubule organization; ISS:HGNC.
 GO:0035021; P:negative regulation of Rac protein signal transduction; ISS:HGNC.
 GO:0031175; P:neuron projection development; ISS:HGNC.
 GO:0051493; P:regulation of cytoskeleton organization; ISS:HGNC.
 GO:0031110; P:regulation of microtubule polymerization or depolymerization; IEA:InterPro.
 GO:0032314; P:regulation of Rac GTPase activity; ISS:HGNC. 
Interpro
 IPR000956; Stathmin_fam. 
Pfam
 PF00836; Stathmin 
SMART
  
PROSITE
 PS00563; STATHMIN_1
 PS01041; STATHMIN_2
 PS51663; STATHMIN_3 
PRINTS
 PR00345; STATHMIN.