UniProt Accession

 TM186_HUMAN; Q96B77; B2RAY0; Q9Y4T4 

Genbank Protein ID

 AL080088; AK314404; CH471112; BC015912 

Genbank Nucleotide ID

 CAB45703.2; BAG37027.1; EAW85205.1; AAH15912.1 

Protein Name

 Transmembrane protein 186 

Protein Synonyms/Alias

  

Gene Name

 TMEM186 

Gene Synonyms/Alias

 C16orf51 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
55	LPNAETEKFWMFYRF	ubiquitination	[1, 2]

Reference

 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Membrane; Reference proteome; Transmembrane; Transmembrane helix. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 213 AA 

Protein Sequence

Gene Ontology

 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005739; C:mitochondrion; IDA:LIFEdb. 

Interpro

 IPR026571; Tmem186. 

Pfam

  

SMART

  

PROSITE

  

PRINTS