CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-031172
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 SH2 domain-containing protein 3A 
Protein Synonyms/Alias
 cDNA FLJ54935, highly similar to SH2 domain-containing protein 3A 
Gene Name
 SH2D3A 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
358LAFEQELKPLMRALDubiquitination[1, 2]
467PRAERFEKFQRVLGVubiquitination[2]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 483 AA 
Protein Sequence
MEKTLLANLG TTASCPARAR KWSNSQPADL AHMGRSREDP AGMEASTMPI SALPRTSSDP 60
VLLKAPAPLG TVADSLRASD GQLQAKAPTK PPRTPSFELP DASERPPTYC ELVPRVPSVQ 120
GTSPSQSCPE PEAPWWEAEE DEEEENRCFT RPQAEISFCP HDAPSCLLGP QNRPLEPQVL 180
HTLRGLFLEH HPGSTALHLL LVDCQATGLL GVTRDQRGNM GVSSGLELLT LPHGHHLRLE 240
LLERHQTLAL AGALAVLGCS GPLEERAAAL RGLVELALAL RPGAAGDLPG LAAVMGALLM 300
PQVRGEQGLE EAGVRVTGKT GEEACSDLFS QVSRLEHTWR QLRRSHTEAA LAFEQELKPL 360
MRALDEGAGP CDPGEVALPH VAPMVRLLEG EEVAGPLDES CERLLRTLHG ARHMVRDAPK 420
FRKVAAQRLR GFRPNPELRE ALTTGFVRRL LWGSRGAGAP RAERFEKFQR VLGVLSQRLE 480
PDR 483 
Gene Ontology
  
Interpro
 IPR023578; Ras_GEF_dom. 
Pfam
  
SMART
  
PROSITE
  
PRINTS