| Tag | Content |
|---|
| CPLM ID | CPLM-007189 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Glutamate synthase [NADPH] large chain |
Protein Synonyms/Alias | NADPH-GOGAT |
Gene Name | gltA |
Gene Synonyms/Alias | BSU18450 |
Created Date | July 27, 2013 |
Organism | Bacillus subtilis (strain 168) |
NCBI Taxa ID | 224308 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 159 | IGASSDLKDNLSFER | acetylation | [1] |
|
Reference | [1] The acetylproteome of Gram-positive model bacterium Bacillus subtilis. Kim D, Yu BJ, Kim JA, Lee YJ, Choi SG, Kang S, Pan JG. Proteomics. 2013 May;13(10-11):1726-36. [ PMID: 23468065] |
Functional Description | |
Sequence Annotation | DOMAIN 22 415 Glutamine amidotransferase type-2.
NP_BIND 1060 1112 FMN (By similarity).
ACT_SITE 22 22 For GATase activity (By similarity).
METAL 1113 1113 Iron-sulfur (3Fe-4S) (By similarity).
METAL 1119 1119 Iron-sulfur (3Fe-4S) (By similarity).
METAL 1124 1124 Iron-sulfur (3Fe-4S) (By similarity). |
Keyword | 3Fe-4S; Amino-acid biosynthesis; Complete proteome; FAD; Flavoprotein; FMN; Glutamate biosynthesis; Glutamine amidotransferase; Iron; Iron-sulfur; Metal-binding; NADP; Oxidoreductase; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 1520 AA |
Protein Sequence | MTYNQMPKAQ GLYRPEFEHD ACGIGLYAHL KGKQTHDIVK QGLKMLCQLD HRGGQGSDPD 60
TGDGAGLLVQ IPDAFFRKEC KNINLPEKER YGVGMVFFSQ KEDERKKIEK QINALIEQEG 120
QVVLGWRTVP VNVGKIGTVA QKSCPFVRQV FIGASSDLKD NLSFERKLYV IRKQAENWGV 180
TEGLDFYFAS LSSQTIVYKG LLTPEQVDAF YSDLQDEAFV SAFALVHSRF STNTFPTWER 240
AHPNRYLVHN GEINTLRGNI NWMRAREQQF VSESFGEDLN KILPILNADG SDSSILDNAF 300
EFFVMAGRKP AHTAMMLIPE PWTENTHMSK EKRAFYEYHS SLMEPWDGPT AISFTDGKQI 360
GAILDRNGLR PARYYVTKDD YIIFSSEVGV IEVEQENVLY KNRLEPGKML LIDLEEGRII 420
SDEEVKTQIA TEYPYQKWLE EELVQVNPDP ESREEEQFSD LLTRQKAFGY TYEDIQKYLI 480
PVIKEGKDPL GSMGNDAPLA VLSDRAQSLF NYFKQLFAQV TNPPIDAIRE QLVTSTMTWL 540
GAEGDLLHPS ERNVRRIKLY TPVLSNEQFY ALKTIVHPDL KSQKIDVLFS EDLERGLKDM 600
FTQAEKAISQ GVSLLILSDK KMNERLTPIP PLLAVSALHQ HLIRKGLRTK VSIIVESGEA 660
REVHHFAALI GYGADAINPY LAYATYKQEI DEGRLDISYE EAVSKYGKSI TEGVVKVMSK 720
MGISTVQSYR GAQIFEAVGI SRDVIDRYFS GTASQLGGID LQTIAEEAQR RHREAYQDDY 780
SKTLEPGSDF QWRNGGEHHA FNPKTIHTLQ WACRRNDYNL FKQYTKAADE ERIGFLRNLF 840
AFDGNRKPLK LEEVESAESI VKRFKTGAMS FGSLSKEAHE ALAIAMNRLG GKSNSGEGGE 900
DPKRFVPDEN GDDRRSAIKQ IASGRFGVKS HYLVNADELQ IKMAQGAKPG EGGQLPGNKV 960
YPWVADVRGS TPGVGLISPP PHHDIYSIED LAQLIHDLKN ANRDARISVK LVSKAGVGTI 1020
AAGVAKATAD VIVISGYDGG TGASPKTSIK HTGLPWELGL AEAHQTLMLN GLRDRVVLET 1080
DGKLMTGRDV VMAALLGAEE FGFATAPLVV LGCVMMRACH LDTCPVGVAT QNPELRKKFM 1140
GDPDHIVNYM LFIAEEVREY MAALGFKTFD EMIGRTDVLH ASERAKEHWK ASQLDLSTLL 1200
YQPEGVRTFQ SPQNHKIDQS LDITTILPAV QEAIESGKEA DISIEINNTN RVAGTITGSE 1260
ISKRYGEEGL PEDTIKLHFT GSAGQSFGAF VPKGMTLYLD GDSNDYVGKG LSGGKIIVKS 1320
SEGFNSASDD NVIIGNVAFY GATSGEAYIN GRAGERFAVR NSGVNVVVEG IGDHGCEYMT 1380
GGSVVVLGDV GKNFAAGMSG GIAYVLTEDV KAFKRKCNLE MILFESLEDE KEIQQIKAML 1440
ERHTAYTNSQ KAEDLLDQWE DSVKKFVKVI PKNYKQMLAS IEEQKAAGLS DEEAIMFAFE 1500
ANTKPKQNTA ASGQKQAVVQ 1520 |
Gene Ontology | GO:0051538; F:3 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW. GO:0004355; F:glutamate synthase (NADPH) activity; IEA:EC. GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW. GO:0097054; P:L-glutamate biosynthetic process; IEA:UniProtKB-UniPathway. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |