| Tag | Content |
|---|
| CPLM ID | CPLM-019804 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | T-complex protein 1 subunit eta |
Protein Synonyms/Alias | TCP-1-eta; CCT-eta; HIV-1 Nef-interacting protein |
Gene Name | CCT7 |
Gene Synonyms/Alias | CCTH; NIP7-1 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 3 | *****MDKLIVDGRG | ubiquitination | [1] |
|
Reference | [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments. Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA. Mol Cell Proteomics. 2013 Mar;12(3):825-31. [ PMID: 23266961] |
Functional Description | Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin (By similarity). |
Sequence Annotation | MOD_RES 1 1 N-acetylmethionine.
MOD_RES 67 67 N6-acetyllysine.
MOD_RES 320 320 N6-acetyllysine. |
Keyword | Acetylation; Alternative splicing; ATP-binding; Chaperone; Complete proteome; Cytoplasm; Direct protein sequencing; Nucleotide-binding; Polymorphism; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 543 AA |
Protein Sequence | MDKLIVDGRG KATISNDGAT ILKLLDVVHP AAKTLVDIAK SQDAEVGDGT TSVTLLAAEF 60
LKQVKPYVEE GLHPQIIIRA FRTATQLAVN KIKEIAVTVK KADKVEQRKL LEKCAMTALS 120
SKLISQQKAF FAKMVVDAVM MLDDLLQLKM IGIKKVQGGA LEDSQLVAGV AFKKTFSYAG 180
FEMQPKKYHN PKIALLNVEL ELKAEKDNAE IRVHTVEDYQ AIVDAEWNIL YDKLEKIHHS 240
GAKVVLSKLP IGDVATQYFA DRDMFCAGRV PEEDLKRTMM ACGGSIQTSV NALSADVLGR 300
CQVFEETQIG GERYNFFTGC PKAKTCTFIL RGGAEQFMEE TERSLHDAIM IVRRAIKNDS 360
VVAGGGAIEM ELSKYLRDYS RTIPGKQQLL IGAYAKALEI IPRQLCDNAG FDATNILNKL 420
RARHAQGGTW YGVDINNEDI ADNFEAFVWE PAMVRINALT AASEAACLIV SVDETIKNPR 480
STVDAPTAAG RGRGRGRPH 499 |
Gene Ontology | GO:0005832; C:chaperonin-containing T-complex; IEA:Compara. GO:0005829; C:cytosol; TAS:Reactome. GO:0005874; C:microtubule; IDA:UniProtKB. GO:0005739; C:mitochondrion; IEA:Compara. GO:0005524; F:ATP binding; IEA:UniProtKB-KW. GO:0051082; F:unfolded protein binding; TAS:ProtInc. GO:0051084; P:'de novo' posttranslational protein folding; TAS:Reactome. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |