CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-039822
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 tRNA pseudouridine synthase 
Protein Synonyms/Alias
  
Gene Name
 PUS1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
316EGKVAAFKEEHIYPTubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Isomerase; Reference proteome; tRNA processing. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 374 AA 
Protein Sequence
MSVAAHTCNL STSGGQRSKR PGVRDQPGQH HGDLCLQNIK SVFVSFFQRN VGSSQFKTIE 60
DDLVSALVRS GCIPENHGED MRKMSFQRCA RTDKGVSAAG QVVSLKVWLI DDILEKINSH 120
LPSHIRILGL KRVTGGFNSK NRCDARTYCY LLPTFAFAHK DRDVQDETYR LSAETLQQVN 180
RLLACYKGTH NFHNFTSQKG PQDPSACRYI LEMYCEEPFV REGLEFAVIR VKGQSFMMHQ 240
IRKMVGLVVA IVKGYAPESV LERSWGTEKV DVPKAPGLGL VLERVHFEKY NQRFGNDGLH 300
EPLDWAQEEG KVAAFKEEHI YPTIIGTERD ERSMAQWLST LPIHNFSATA LTAGGTGAKV 360
PSPLEGSEGD GDTD 374 
Gene Ontology
 GO:0009982; F:pseudouridine synthase activity; IEA:InterPro.
 GO:0003723; F:RNA binding; IEA:InterPro.
 GO:0001522; P:pseudouridine synthesis; IEA:InterPro.
 GO:0008033; P:tRNA processing; IEA:UniProtKB-KW. 
Interpro
 IPR020103; PsdUridine_synth_cat_dom.
 IPR001406; PsdUridine_synth_TruA.
 IPR020097; PsdUridine_synth_TruA_a/b_dom.
 IPR020095; PsdUridine_synth_TruA_C.
 IPR020094; PsdUridine_synth_TruA_N. 
Pfam
 PF01416; PseudoU_synth_1 
SMART
  
PROSITE
  
PRINTS