CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027977
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 ALG-2 interacting protein X 
Protein Synonyms/Alias
 LD25543p 
Gene Name
 ALiX 
Gene Synonyms/Alias
 CG12876; Dmel_CG12876 
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
100KWKDAFDKGSIFGGKacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 836 AA 
Protein Sequence
MSKFLGVPLK KPSEVDVIKP LNNLIQSTYN GASEEEKGKY GEAVNEFSKQ RNTAIWKFFE 60
KYEASLEIVY AYYDQICALE TKISVSELQI PFKWKDAFDK GSIFGGKISL THTSLLYEKV 120
CVLFNIAALQ SNIAANQSLD SDDGLKLTIK LLQQSAGIFQ YLKGATPAAV PSEPTPDLSQ 180
DTLTVLQALM VAQAQEVFIL KAIKDNLKDQ IIAKLCCQAE ESYADVLRAM QKESVRSLWE 240
KEWIPTIAGK QAGFHALTQL YQSLVCRAAK KIGEEIARLR NAIDLFKAAQ TRSGNETYLD 300
EYFSRAKRNL TESTKDNEFI YNEIIPELST LTSPGKAQLA KPLPIAVPLA ENFKDIFSSL 360
VPVELHRALT ASDMRRNEIV NVEIMKLREA TQTLNAVLAS LNLPAAVETA DGNSGLPPSL 420
KEKANEVRQK GGIENVQTML KDLPELLNRN REILDETERL LDEERDSDNQ LRAQFKDRWT 480
RISSDKLTEM FRTNAKKYRE VITNAIEADK VVRQKFEANQ KGIQLLSLPP DQIQQSLPSA 540
SGSVDPNCSS VQRLKKLMDD VETIKAEREA IESELKGATF NMKDEFLIAL QKDGAIDEPA 600
LSLARIGQVL NPLQQQVRES VERQQSLVSE IQSAHGAFVS ETGSCGSSRD TLYQELATAF 660
DSYIELSGNL QEGTKFYNDL TQLLVVFQNK ISDFVFARKT EKEELLKDLT TESSRQACPA 720
TPALPSHYAS TSGSGSDIPP GSAPSVPPAA STANIPYPAQ VQGMPIPYGA QPGVPYPAYV 780
PAPMPQSFNP YATLPYPGNY QYQGFPQGPP PGHYGTYPGS YANQQGGYPN QKPPGW 836 
Gene Ontology
 GO:0030041; P:actin filament polymerization; IMP:FlyBase.
 GO:0046330; P:positive regulation of JNK cascade; IDA:FlyBase. 
Interpro
 IPR025304; ALIX_V_dom.
 IPR004328; BRO1_dom. 
Pfam
 PF13949; ALIX_LYPXL_bnd
 PF03097; BRO1 
SMART
 SM01041; BRO1 
PROSITE
 PS51180; BRO1 
PRINTS