Tag | Content |
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CPLM ID | CPLM-023401 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Protein purity of essence |
Protein Synonyms/Alias | Interaction calmodulin and colossal molecular mass protein; Protein Calossin; Protein pushover |
Gene Name | poe |
Gene Synonyms/Alias | calo; push; CG14472 |
Created Date | July 27, 2013 |
Organism | Drosophila melanogaster (Fruit fly) |
NCBI Taxa ID | 7227 |
Lysine Modification | Position | Peptide | Type | References |
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27 | NRTGALNKNEVVNLL | acetylation | [1] | 3947 | TSFEELSKIVQKVKA | acetylation | [1] |
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Reference | [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation. Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C. Sci Signal. 2011 Jul 26;4(183):ra48. [ PMID: 21791702] |
Functional Description | Has a role in growth of the perineurial glial layer of the larval peripheral nerve. May have a role in male fertility and eye development or function. |
Sequence Annotation | ZN_FING 1794 1863 UBR-type. MOD_RES 167 167 Phosphoserine. MOD_RES 599 599 Phosphothreonine. MOD_RES 600 600 Phosphoserine. MOD_RES 1167 1167 Phosphoserine. MOD_RES 1168 1168 Phosphoserine. MOD_RES 1171 1171 Phosphoserine. MOD_RES 1894 1894 Phosphoserine. MOD_RES 3013 3013 Phosphothreonine. MOD_RES 3014 3014 Phosphoserine. MOD_RES 3051 3051 Phosphoserine. MOD_RES 3057 3057 Phosphoserine. MOD_RES 3510 3510 Phosphoserine. |
Keyword | Alternative splicing; Calmodulin-binding; Complete proteome; Developmental protein; Differentiation; Metal-binding; Neurogenesis; Phosphoprotein; Reference proteome; Sensory transduction; Vision; Zinc; Zinc-finger. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 5322 AA |
Protein Sequence | MSAHSGGTDW NSVVKALILN RTGALNKNEV VNLLKAITRC EHDFFEEESN FTQFYTAFAA 60 LAADKLMQIK TICQTQICQL HDATAVLIRF IIYRLPRVSV YETKWLLGAL KMLCEGRECP 120 ASASSSMFDY NAVANVLKSC KHPESTTKSI MPSSSSSGSG ASNDKESPKS EIKRSRSDLS 180 SVILQQLIAP LEPGKMTWVP LSEEVTDCTE QILAANVEYF QEQNGVDTLL DVCVSLPILN 240 RYRSKYMETI NGGKSLYLPL TQVEATAVKS SMNHMLTDLT ILSQAQALIE MQPLTPSRIE 300 RLSMCGIAAL YNAVLTSIAT SVLGMSQASS SQKQTASTSQ GSGVGGSSGG QSNKDHDDFE 360 DQACSIVNKA LEIYSNIGHM FKTSARIHVY QNHLCYGSWL LISGIQGAMG ASGSGGSSSD 420 SASKSASKAT KSGSEAGTAP TTPIARVNLF KVQQGFGELN AAIANHSIKL LSELIEDLKV 480 EAACGQSLES TELPEPAQFD ILQNYSSLER IVRVLNTATL HQLFTFLATV AYRKACTLKR 540 ASAKDRTECE PISYSDSTTY FNDSLSCSDN SEEDDSESYL GHWFKETLSP ETHDDNANTS 600 TQERAEQKSA LVPKLDEPHE YLDLAADIFC FLDQFLANRH AYMQRYVKAG VSDQQMLLMA 660 NIIKDFDRDV MRNESDQGSG NAPAASAGAG TSAGASTKWQ TSMIRFSGAA GRYIHNLIST 720 SLLSEQLQSN LLQHLSISPW STDTNTWPLQ VYPSTLSVLV QILLLKPTQE KEAACLSVWH 780 RLINTLVEGV CSSNTASDSD YEDLNIEHAQ LLLFLFHSLN LMQKKSILLL TAGGVIRCAE 840 VCRGISEDRP VKNSQIMLLS RLLLFLEYLM KHLYNAPPEL LDQVRWNLFS VSSMPDTQKI 900 TDLLNCRTKL NSYCRHDIEE NFRKSAGEYG SSIRPTFYSL VMGDPEISYW AQEFKLDGLA 960 WNFILCTPDK LKYPLLVDAL TDILSITDMS MYSKEKDKEA SMHNLCAIQY CFTIAWKLNL 1020 GLPPSTSHVE SLKAERSPNL HSLMWSIRLP LASSHYLVVS SLIKQGMYTQ YAETLWTHVG 1080 DIGADIKYSL KQTILGVEAF NSQMNGNGTP RLSDLILFDS LVAHMQAVAW ANKEGLKWPR 1140 KESEDAAGEQ SAGTSLTSSS NDPELYSSNE SIDDQKLKQD DDGKLSSDLQ KYNQLVNELM 1200 VKLMNSYQLL SVIVRGQMLK QLSSSTPEKA LNLIVPIVSD KPAIMLELHA AFLKLLPNED 1260 KQLIANEWPK CLMVNDFAFN GKQHPVEPYI LNVIDAHIIE LTRGSNYSTL HTLKHCLKSI 1320 LQLFELLLPH RTANAEVETQ LKQLLISSML DMRTDYLQGH SEHCLREILS GLTQEAQKLL 1380 LYEHMVGYCY RMLKEFAADL RQPQSAGPSG GAPLDQDRAM FNESMLFAVL KTMFKMLEKP 1440 VAVQAMRQFF KDQRSGSLTT LLLSFTGTSL PVSYARKMLQ FVNRLFQLSL QADSQFQHED 1500 LVECFSELAT VDVARLKQWL GHIIYGPNVS TDVSTSEALD TTCRMLTSIL QPSSSSSSNA 1560 QTPTNMATVS AMPSISDQLD PMEIEYDCGT AAGGGESNPG TGGAAANTSQ ILSLWQAAQP 1620 NPSEESSQAC DHSDSERNGA LLLSFVKSLV KDQSKASQIA PPLFQALLQL GQTLISPPQE 1680 GCDFADVLQI MITLADASPA RGHVALFNTT LLWLELAKLQ LPDKHLKHAE NVSAQLRYLS 1740 ELLQSIGFRG SRQHNPPWDD ELQTDIDELY DELAEEGEQD SLLDDSDEDT LNNKLCTFSQ 1800 TQKEFMNQHW YHCHTCNMIN TVGVCSVCAR VCHKGHDVSY AKYGNFFCDC GAKEDGSCQA 1860 LSRRIGSNEV RDSAGIGSYL PSHMSLLAGK KRSSLPVGQP VLTRKDSLTN ERIAVLTKLL 1920 EPYRETLQHQ DQWLLVVRCI LEYFDLLLPS INENCMLYSI VGCHKRATAA LERLHLLEQS 1980 FQVTDQLMFA TLGSQEGAFE NVRMNYSGDQ GQTIKHLLSS GVVRRVAFCC LSSPHGRRQQ 2040 LAVSHEKGKV TILQLSALLK QADASKRKLT LTQLSSAPIA CTVISLAANP CNEDCLAVCG 2100 LKECHILTFS SSGSTNEHIV VNPQLENGNY IKKAVWLPGS QTLLAVVTSD YVKIYDLAVD 2160 TYSPKYYYLV AVGKIRDCTF VYQDGNYNML TFASSGYIYT QQLDQQSLAV HGDFYVTNTL 2220 ELSHQHIKDI AGHIGGGGVS IYYSHTLQLL FYSYSCGRSF FSPLTNVSEG VKGIYHLDTN 2280 SASKSASKGP LQPLVQWTEV TGHPGLVYAS MQTSNNPIIL MITPERIYLQ EIKAQSAKSR 2340 IMDVVGIRHA VAGVEKTTLL LLCEDGSLRI FSAQPEYTSF WLSPQVQPFG NQLYSSTLMA 2400 KGGGSGSTSK SKSNTASGKM TSRKASQQQK QPTAGGQPVF PIDFFEHCNM LADVEFGGND 2460 LLQIYNKQKL KTRLFSTGMF VASTRSNGFT LEVINNDPNV VIVGIRVLIG TQDVQRAPQS 2520 VTILGRTIPT PVRRARWFDI PLTREEMLQS DKLLKVVFAK APDPEHVTLL DCIEVYGKSK 2580 ELVGWPDESE DVTVPGSSAP AVSSSQASSA NFGEGFNCIT QLDRMANHLL EVMDCALHLL 2640 GSGVPASMRQ KAVKTASALL LLPTPNPVQT QARYVLATLY GTRALYHNYK DGVLLQFVNR 2700 ELQSMQPKLE KLETLREIDP EAFYRLVLMV RGIANARPQS LAKICVENNY DIVPTLMGIV 2760 LELHKVTPTL DEPVNIVKRG LCQPETIVHC LVEIMYGFAL ADPGQVGRMT KYFIDLLKHD 2820 ASVISHSAKE ALILLLSPRM KRRKVAIVTP PACSTPTPST STMQALQAAA SSAASDIIEE 2880 AAGVVVDGSV GGGGLPEPNA DAEGAAVGVG GVGQQQMLNL EAFMGGGFPR LLGLPEDADD 2940 EAIMDIAIAL SLQQHGGDAN ALQSLQQGLA NLQGIRQATA MAAAVNAAAN VSLGGSDDDE 3000 GSNVATDGST LRTSPAEPAG SGGSESGGSG VESIGGTSAR SSNFGDHANA SPPRQGSTKD 3060 DQEQPGPSGV AGSGGVAVLS AMSSSEDNEA NEDDKLSKLH DLRIAVLESI IQHLGTFDLC 3120 NGLQAIPLIQ VILMLTTDLN GNNERDQQVL HDLLTALVDY VEIGKRGAAA RMETKCPGNE 3180 VRLALLSLFG VLMGKTKSKQ TGTTSPPHQF KDNSSFVAST TANVLSKSGA FVYALEALNT 3240 LLVHWKNVLG DPYAAGGGLA SQSAQASGGA SGPGVQLLKP IKHGPKPDIS ILIPHNYLKN 3300 YPDIFESYDG LLTEIIVRLP YQILRLSSAH PDNYDSGFCE AMTFTLCEYM MLNLNTLLRR 3360 QVRKLLMYIC GSKEKFRMYR DGHSLDAHFR VVKRVCNIVS SKTGAPYNAN PPMLSYDALV 3420 ELTEHLRTCQ EISQMRTGNW QKFCVVHEDA LAMLMEIACY QLDDGVSPII IQLLQAAVCN 3480 LPPPSGSKQA QPQPSTSSAS GKLRTDREKS EDTDAYYSKF DPAQCGTFVH QIFRYACDAL 3540 IIRFVRIFLL ENNITQLRWQ AHSFMTGLFE HANERQREKL LNIFWNLWPL VPTYGRRTAQ 3600 FVDLLGYLTL STRSITERLP EFVSRAVDVL RQQNELLCKH PNAPIYTTLE SILQVNGYYL 3660 ESEPCLVCNN PEVPMANIKL PSVKSDSKYT TTTMIYKLVQ CHTISKLIVR IADLKRTKMV 3720 RTINVYYNNR SVQAVVELKN RPALWHKARS VSLQSAQTEL KIDFPLPITA CNLMIEFADF 3780 FETVSGSSEN LQCPRCSAAV PAYPGVCGNC GENVFQCHKC RAINYDEKDP FLCHSCGFCK 3840 YAKFDFSMYA RVCCAVDPIE SAEDRVKTVS LIHSSLERAD RNYRQLLTNK QMLELLIQKV 3900 AEHRSSDRMV EDNMASVHST SQVNKIIQLL AQKYCVESRT SFEELSKIVQ KVKACRSELV 3960 AYDRQQQDQP PVNPGSTTGA ENPTTNRCYG CALASTEQCL TLLRAMAYNY DCRVCLYSQG 4020 LVSELAEHNL RRGTPLIQEE VRNLLVVLTK DNAEACMHLL QLVTTRVKNA LMGSIPLISL 4080 EAAVHQEMTL LEVLLGQDDI CWEYKLKVIF ELFISNCRLP RGPVTAVLHP CLRIMQNLIC 4140 PVLPGSKPNQ KVATTDLCSM KMFEGNTVDY RAWLNSDRNH EYAAWSKRMP SNNQAKLKNA 4200 KDQNVAASGG SDAPPKSRRE VRVAFLSEKY GKRWRERVLD KQRVIKPLVF NAKWIQPLLF 4260 NANSRFGRQL ACSLLSSLSR TNERRQQALN MLTSFLKHVG EAGEASAEYL MLYKNMATEQ 4320 PWLQYLVLKG VLSQISQLLA IEISKVHRME EYSLSSDLSL GYALRQYVEL LWLLLECPNI 4380 RRTYKTRMLG PVLESYLALR SLVVQRTRLI DDAQEKLLEM LEDMTSGTEE ETRAFMEILI 4440 DTVEKTRMND IKTPVFVFER LYSIIHPEEH DESEFYMTLE KDPQQEDFLQ GRMLGNPYPS 4500 SEMGLGPLMR DVKNKICTDC ELIALLEDDN GMELLVNNKI ISLDLPVKDV YKKVWLAEGG 4560 DRDAMRIVYR MRGLLGDATE EFVETLNNKS QEQVDTEQLY RMANVLADCN GLRVMLERIG 4620 SLQRISRNRE LIQVLLKLFL ICVKVRRCQE VLCQPEIGAI NTLLKVLQMC LQSENDSIQS 4680 AVTEQLLEIM ETILSKAASD TLDSFLQFSL TFGGPEYVSA LISCTDCPNV RNNPSVLRHL 4740 IRVLAALVYG NEVKMALLCE HFKDTLNFNR FDNERTPEEE FKLELFCVLT NQIEHNCIGG 4800 TLKDYIVSLG IVERSLAYIT EHAPCVKPTL LRTDSDELKE FISRPSLKYI LRFLTGLSNH 4860 HEATQVAISK DIIPIIHRLE QVSSDEHVGS LAENLLEALS TDSATAARVQ QVRDFTRAEK 4920 KRLAMATREK QLDALGMRTN EKGQVTAKGS ILQKIEKLRD ETGLTCFICR EGYACQPDKV 4980 LGIYTFTKRC NVEEFELKSR KTIGYTTVTH FNVVHVDCHT SAIRLTRGRD EWERASLQNA 5040 NTRCNGLLPL WGPAVGEAAF SACMTRHSSY MQESTQRCDI SYTSSVHDLK LLLVRFAWER 5100 SFHDDAGGGG PQSNMHFVPY LLFYSVYLLL SSRSAARDSK TLLTYLQAPP SEKWLECGYE 5160 VDGPLFMATI SLSLHSRELW NKHKLAHLKR MIAVAQGRHV SPAVLCKALL APADRQVKDY 5220 TVYKPFLMMW ALVDLIYDNL FKTVSTPKEE DWPISLFDYL RKNDEALLKS TDSILQTLTE 5280 EFLPCTSFVE FCDVAGLLHL IEHPDNFIEE ILAALPSTSS SN 5322 |
Gene Ontology | GO:0005516; F:calmodulin binding; NAS:UniProtKB. GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro. GO:0008270; F:zinc ion binding; IEA:InterPro. GO:0042066; P:perineurial glial growth; IMP:FlyBase. GO:0016567; P:protein ubiquitination; IEA:GOC. GO:0050896; P:response to stimulus; IEA:UniProtKB-KW. GO:0007291; P:sperm individualization; IMP:FlyBase. GO:0007601; P:visual perception; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |