CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-028498
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Arginine-glutamic acid dipeptide repeats protein 
Protein Synonyms/Alias
  
Gene Name
 Rere 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
110ESSYDAGKALQRLVKubiquitination[1]
882FMPLAGSKLAKKREEacetylation[2, 3]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441]
 [3] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1290 AA 
Protein Sequence
MDDPFSPCRR LNSTQGEIRV GPSHQAKLPD LQPFPSPDGD TVTQHEELVW MPGVSDCDLL 60
MYLRAARSMA AFAGMCDGGS TEDGCVAASR DDTTLNALNT LHESSYDAGK ALQRLVKKPV 120
PKLIEKCWTE DEVKRFVKGL RQYGKNFFRI RKELLPSKET GELITFYYYW KKTPEAASSR 180
AHRRHRRQAV FRRIKTRTAS TPVNTPSRPP SSEFLDLSSA SEDDFDSEDS EQELKGYACR 240
HCFTTTSKDW HHGGRENILL CTDCRIHFKK YGELPPIEKP VDPPPFMFKP VKEEDDGLSG 300
KHSMRTRRSR GSMSTLRSGR KKQPTSPDGR ASPINEDIRS SGRNSPSAAS TSSNDSKAET 360
VKKSAKKVKE EAASPLKSTK RQREKVASDT EDTDRITSKK TKTQEISRPN SPSEGEGESS 420
DSRSVNDEGS SDPKDIDQDN RSTSPSIPSP QDNESDSDSS AQQQMLQAQP PALQAPSGAA 480
SAPSTAPPGT PQLPTQGPTP SATAVPPQGS PATSQPPNQT QSTVAPAAHT HIQQAPTLHP 540
PRLPSPHPPL QPMTAPPSQS SAQPHPQPSL HSQGPPGPHS LQTGPLLQHP GPPQPFGLPS 600
QPSQGQGPLG PSPAAAHPHS TIQLPASQSA LQPQQPPREQ PLPPAPLAMP HIKPPPTTPI 660
PQLPAPQAHK HPPHLSGPSP FSLNANLPPP PALKPLSSLS THHPPSAHPP PLQLMPQSQP 720
LPSSPAQPPG LTQSQSLPPP AASHPTTGLH QVPSQSPFPQ HPFVPGGPPP ITPPSCPPTS 780
TPPAGPSSSS QPPCSAAVSS GGSVPGAPSC PLPAVQIKEE ALDEAEEPES PPPPPRSPSP 840
EPTVVDTPSH ASQSARFYKH LDRGYNSCAR TDLYFMPLAG SKLAKKREEA IEKAKREAEQ 900
KAREEREREK EKEKERERER EREREAERAA KASSSAHEGR LSDPQLSGPG HMRPSFEPPP 960
TTIAAVPPYI GPDTPALRTL SEYARPHVMS PTNRNHPFYM PLNPTDPLLA YHMPGLYNVD 1020
PTIRERELRE REIREREIRE RELRERMKPG FEVKPPELDP LHPATNPMEH FARHSALTIP 1080
PAAGPHPFAS FHPGLNPLER ERLALAGPQL RPEMSYPDRL AAERIHAERM ASLTSDPLAR 1140
LQMFNVTPHH HQHSHIHSHL HLHQQDPLHQ GSAGPVHPLV DPLTAGPHLA RFPYPPGTLP 1200
NPLLGQPPHE HEMLRHPVFG TPYPRDLPGA IPPPMSAAHQ LQAMHAQSAE LQRLAMEQQW 1260
LHGHPHMHGG HLPSQEDYYS RLKKEGDKQL 1290 
Gene Ontology
 GO:0000118; C:histone deacetylase complex; IPI:MGI.
 GO:0003682; F:chromatin binding; IEA:InterPro.
 GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
 GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0006338; P:chromatin remodeling; IPI:MGI. 
Interpro
 IPR002951; Atrophin-like.
 IPR000949; ELM2_dom.
 IPR009057; Homeodomain-like.
 IPR001005; SANT/Myb.
 IPR017884; SANT_dom.
 IPR000679; Znf_GATA. 
Pfam
 PF03154; Atrophin-1
 PF01448; ELM2
 PF00320; GATA 
SMART
 SM00717; SANT
 SM00401; ZnF_GATA 
PROSITE
 PS51156; ELM2
 PS51293; SANT 
PRINTS