UniProt Accession

 D3YTM5_MOUSE; D3YTM5 

Genbank Protein ID

 AC117698; AC125065 

Genbank Nucleotide ID

  

Protein Name

 cAMP-dependent protein kinase type I-beta regulatory subunit 

Protein Synonyms/Alias

  

Gene Name

 Prkar1b 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
56	FLREHFEKLEKEENR	acetylation	[1]
92	TPPNPVVKARRRRGG	ubiquitination	[2]
222	VKAKTDLKLWGIDRD	ubiquitination	[2]

Reference

 [1] Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways.
 Rardin MJ, Newman JC, Held JM, Cusack MP, Sorensen DJ, Li B, Schilling B, Mooney SD, Kahn CR, Verdin E, Gibson BW.
 Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):6601-6. [PMID: 23576753]
 [2] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 235 AA 

Protein Sequence

Gene Ontology

 GO:0005952; C:cAMP-dependent protein kinase complex; IEA:InterPro.
 GO:0005737; C:cytoplasm; TAS:MGI.
 GO:0008603; F:cAMP-dependent protein kinase regulator activity; ISS:MGI.
 GO:0008283; P:cell proliferation; TAS:MGI.
 GO:0007611; P:learning or memory; IMP:MGI.
 GO:0009887; P:organ morphogenesis; TAS:MGI.
 GO:0006468; P:protein phosphorylation; TAS:MGI.
 GO:0007165; P:signal transduction; IEA:InterPro. 

Interpro

 IPR002373; cAMP/cGMP_kin.
 IPR003117; cAMP_dep_PK_reg_su_I/II_a/b.
 IPR018490; cNMP-bd-like.
 IPR018488; cNMP-bd_CS.
 IPR000595; cNMP-bd_dom.
 IPR014710; RmlC-like_jellyroll. 

Pfam

 PF00027; cNMP_binding
 PF02197; RIIa 

SMART

 SM00100; cNMP
 SM00394; RIIa 

PROSITE

 PS00888; CNMP_BINDING_1
 PS00889; CNMP_BINDING_2
 PS50042; CNMP_BINDING_3 

PRINTS

 PR00103; CAMPKINASE.