CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-039334
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein Myh13 
Protein Synonyms/Alias
  
Gene Name
 Myh13 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
609TVVGLYQKSSLKLLSacetylation[1]
835PWMNLFFKIKPLLKSacetylation[1]
876RRKELEEKMVSLLQEacetylation[1]
1872LVDKLQAKVKSYKRQacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Actin-binding; ATP-binding; Coiled coil; Complete proteome; Motor protein; Myosin; Nucleotide-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1932 AA 
Protein Sequence
MSTDAEMAIF GEAAPYLRKP EKERIEAQNR PFDSKKACFA VDDKEMYVKG MIQSRENDKV 60
IVKTLDDREL TLNSDQVFPM NPPKFDKIED MAMMTHLHEP AVLYNLKERY AAWMIYTYSG 120
LFCVTVNPYK WLPVYNPEVV TAYRGKKRQE APPHIFSISD NAYQFMLTDR DNQSILITGE 180
SGAGKTVNTK RVIQYFATIA VTGEKKKEQQ PGKMQGTLED QIIQANPLLE AFGNAKTVRN 240
DNSSRFVRAD WFSTPHPIAP LLNSRCENSL QRLRYTDERS YHIFYQIMSN KKPELIDLLL 300
ISTNPFDFPF VSQGEVTVAS IDDSEELLAT DNAIDILGFS PEEKVGIYKL TGAVMHYGNM 360
KFKQKQREEQ AEPDGTEVAD KAGYLMGLNS AEMLKGLCCP RVKVGNEYVT KGQNVQQVTN 420
SVGALAKAVY EKMFLWMVTR INQQLDTKQP RQYFIGVLDI AGFEIFDFNS LEQLCINFTN 480
EKLQQFFNHH MFVLEQEEYK KEGIEWEFID FGMDLAACIE LIEKPMGIFS ILEEECMFPK 540
ATDTSFKNKL YDQHLGKSNN FQKPKPAKGK AEAHFSLVHY AGTVDYNIAG WLDKNKDPLN 600
ETVVGLYQKS SLKLLSFLFS NYAGAEAGDS TGGKKGGKKK GSSFQTVSAV FRENLNKLMT 660
NLRSTHPHFV RCLIPNETKT PGVMDHYLVM HQLRCNGVLE GIRICRKGFP SRILYADFKQ 720
RYRILNASAI PEGQFIDSKN ASEKLLNSID VDREQFRFGH TKVFFKAGLL GLLEEMRDEK 780
LVTLMTRTQA VCRGYLMRVE FKKMMERREA IFCIQYNVRS FMNVKHWPWM NLFFKIKPLL 840
KSAEAEKEMA TMKEDFERAK EELARSEARR KELEEKMVSL LQEKNDLQLQ VQSETENLMD 900
AEERCEGLIK SKIQLEAKVK ELNERLEEEE ETNSELVAKK RNLEDKCSSL KRDIDDLELT 960
LTKVEKEKHA TENKVKNLSE EMTALEETIS KLTKEKKSLQ EAHQQTLDDL QVEEDKVNGL 1020
MKINVKLEQQ TDDLEGSLEQ EKKLRADLER VKRKLEGDLK MSQESIMDLE NDAQQLEEKL 1080
KKKEFEMSQL QTRIDDEQIL SLQLQKKIKE LQARTEELEE EIEAEHTVRA KIEKQRSDLA 1140
RELEEISERL EEASGATSAQ IEMNKKREAE FQKLRRDLEE ATLQHEATAA TLRKKHADTV 1200
AELGEQIDNL QRVKQKLEKE KSELKMEIDD MASNIEAVSK SKSNMERMCR SVEDQFNEIK 1260
AKDDQQTQLI HDLNMQKARL QTQNGELNHQ VEEKESLVSQ LTKSKQALTQ QLEELKRQLE 1320
EETKAKNALA HALQSSRHDC DLLREQYEEE QEGKAELQRA LSKANSEVAQ WRTKYETDAI 1380
QRTEELEEAK KKLAQRLQEA EENTEASNSK CASLEKTKQR LQGEVDDLML DLEKANTACA 1440
TLDKKQRNFD KVLAEWKQKL DESQAELEAA QKESRSLSTE IFKMRNAYEE VVDQLETLRR 1500
ENKNLQEEIS DLTEQIAETG KNLQEVEKTK KQMEQEKSDL QAALEEVSGS LEHEESKILR 1560
VQLELSQVKS ELDRKVTEKD EEIEQIKRNS QRAVEAMQSV LDAEIRSRND ALRLKKKMEG 1620
DLNEMEIQLS HANRQVAETQ KHLRTVQGQL KDSQLHLDDA QRSNEDLKEQ LAIVERRNGL 1680
LQEELEEMKV ALEQTERTRR LSEQELLDSS DRVQLLHSQV RCLLNSVAQP DAFSPQETTP 1740
QHRTPPPHGP REEGVGTGMA KCGPWGEDLK KEDVLFDIEP KGSLLPLGTF KVELIVCERK 1800
LAALTSLLGY TLYPTQVREL ESELDAEQKR GAEALKGAHK YERKVKEMTY QAEEDRKNIL 1860
RLQDLVDKLQ AKVKSYKRQA EEAEEQANTQ LSRCRRVQHE LEEAEERADI AESQVNKLRA 1920
KSRDVGGQKM EE 1932 
Gene Ontology
 GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0003774; F:motor activity; IEA:InterPro. 
Interpro
 IPR000048; IQ_motif_EF-hand-BS.
 IPR027401; Myosin-like_IQ_dom.
 IPR015650; Myosin_1/23/4/7/8/13/15.
 IPR001609; Myosin_head_motor_dom.
 IPR004009; Myosin_N.
 IPR002928; Myosin_tail.
 IPR027417; P-loop_NTPase. 
Pfam
 PF00063; Myosin_head
 PF02736; Myosin_N
 PF01576; Myosin_tail_1 
SMART
 SM00015; IQ
 SM00242; MYSc 
PROSITE
 PS50096; IQ 
PRINTS
 PR00193; MYOSINHEAVY.