UniProt Accession

 DC2L1_HUMAN; Q8TCX1; A8MVJ5; Q53F57; Q6PDB2; Q8IWA3; Q96B03; Q96J00; Q9Y370; Q9Y3S9 

Genbank Protein ID

 AY083346; AF151818; AK223432; AC011242; CH471053; CH471053; CH471053; BC006969; BC016324; BC040558; BC058823; AL050006 

Genbank Nucleotide ID

 AAL99216.1; AAD34055.1; BAD97152.1; AAY14702.1; EAX00289.1; EAX00290.1; EAX00291.1; AAH06969.1; AAH16324.1; AAH40558.1; AAH58823.1; CAB43233.1 

Protein Name

 Cytoplasmic dynein 2 light intermediate chain 1 

Protein Synonyms/Alias

 Dynein 2 light intermediate chain 

Gene Name

 DYNC2LI1 

Gene Synonyms/Alias

 D2LIC; LIC3; CGI-60 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
329	VDEMRIQKDLELEQY	ubiquitination	[1]

Reference

 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473] 

Functional Description

 May function as a motor for intraflagellar retrograde transport. Functions in cilia biogenesis (By similarity). 

Sequence Annotation

  

Keyword

 Alternative splicing; Cell projection; Cilium; Cilium biogenesis/degradation; Complete proteome; Cytoplasm; Cytoskeleton; Developmental protein; Dynein; Microtubule; Motor protein; Polymorphism; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 351 AA 

Protein Sequence

Gene Ontology

 GO:0045177; C:apical part of cell; ISS:BHF-UCL.
 GO:0005858; C:axonemal dynein complex; ISS:BHF-UCL.
 GO:0035085; C:cilium axoneme; ISS:BHF-UCL.
 GO:0005829; C:cytosol; TAS:Reactome.
 GO:0030990; C:intraflagellar transport particle; IEA:Compara.
 GO:0005874; C:microtubule; IEA:UniProtKB-KW.
 GO:0031512; C:motile primary cilium; ISS:BHF-UCL.
 GO:0003774; F:motor activity; IEA:UniProtKB-KW.
 GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
 GO:0042384; P:cilium assembly; IEA:Compara.
 GO:0007368; P:determination of left/right symmetry; IEA:Compara. 

Interpro

 IPR022780; Dynein_light_int_chain.
 IPR027417; P-loop_NTPase. 

Pfam

 PF05783; DLIC 

SMART

  

PROSITE

  

PRINTS