CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038265
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Synaptotagmin-7 
Protein Synonyms/Alias
  
Gene Name
 Syt7 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
50RKLGKRYKNSLETVGubiquitination[1]
192RNRGLDMKSFLEGRMubiquitination[1]
347KIYLLPDKKHKLETKubiquitination[1]
377FEGFPYEKVVQRVLYubiquitination[1]
458IIKARNLKAMDIGGTubiquitination[1]
539GKIYLSWKSGPGEVKubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 567 AA 
Protein Sequence
MYRDPEAASP GAPTRDVLLV SAIITVSLSV TIVLCGLCHW CQRKLGKRYK NSLETVGTPD 60
SGRGRGEKKA INFEDSTLST ATTLESIPSS AGEPKCQRPR TLMRQQSLQQ PLSQNQQGRQ 120
PSQPTTSQSL GQLQAHAASA PGSNPRAYGR GQARQGTSAG SKYRAAGGRS RSNPGSWDHV 180
VGQIRNRGLD MKSFLEGRMV VLSLVLGLSE QDDFANIPDL QNPGTQQNQN AQGDKRLPAG 240
GKAVNTAPVP GQTPHDESDR RTETRSSVSD LVNSLTSEML MLSPGSEEDE AHEGCSRENL 300
GRIQFSVGYN FQESTLTVKV MKAQELPAKD FSGTSDPFVK IYLLPDKKHK LETKVKRKNL 360
NPHWNETFLF EGFPYEKVVQ RVLYLQVLDY DRFSRNDPIG EVSIPLNKVD LTQMQTFWKD 420
LKPCSDGSGS RGELLLSLCY NPSANSIIVN IIKARNLKAM DIGGTSDPYV KVWLMYKDKR 480
VEKKKTVTKK RNLNPIFNES FAFDIPTEKL RETTIIITVM DKDKLSRNDV IGKIYLSWKS 540
GPGEVKHWKD MIARPRQPVA QWHQLKA 567 
Gene Ontology
 GO:0005764; C:lysosome; IDA:MGI.
 GO:0005886; C:plasma membrane; IEA:Compara.
 GO:0008021; C:synaptic vesicle; IEA:InterPro.
 GO:0005509; F:calcium ion binding; IEA:Compara.
 GO:0005215; F:transporter activity; IEA:InterPro.
 GO:0001778; P:plasma membrane repair; IDA:MGI.
 GO:0017158; P:regulation of calcium ion-dependent exocytosis; IEA:Compara.
 GO:0050796; P:regulation of insulin secretion; IEA:Compara. 
Interpro
 IPR000008; C2_Ca-dep.
 IPR008973; C2_Ca/lipid-bd_dom_CaLB.
 IPR020477; C2_dom.
 IPR018029; C2_membr_targeting.
 IPR001565; Synaptotagmin.
 IPR015427; Synaptotagmin7. 
Pfam
 PF00168; C2 
SMART
 SM00239; C2 
PROSITE
 PS50004; C2 
PRINTS
 PR00360; C2DOMAIN.
 PR00399; SYNAPTOTAGMN.