| Tag | Content |
|---|
| CPLM ID | CPLM-017785 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Vacuolar protein sorting-associated protein 37B |
Protein Synonyms/Alias | Vps37B; ESCRT-I complex subunit VPS37B |
Gene Name | Vps37b |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 45 | AQTVQLNKEMTLASN | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation (By similarity). |
Sequence Annotation | DOMAIN 84 173 VPS37 C-terminal.
REGION 50 170 Interaction with IST1 (By similarity). |
Keyword | Complete proteome; Endosome; Membrane; Protein transport; Reference proteome; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 285 AA |
Protein Sequence | MAGAVSEARF AGLSLMQLHE LLEDDAQLGD MVRGMEEAQT VQLNKEMTLA SNRSLAEGNL 60
LYQPQLDAQK ARLTQKYQEL QVLFEAYQIK KTKLDKQSNN ASLETLLALL QAEGAKIEED 120
TENMAEKFLD GELPLDSFID VYQSKRKLAH MRRVKVEKLQ ELVLKGQRHP QAGAPPPPRV 180
PEPSPATALP YPSLEATGLP SVVPRRIPPP PPPVPAGHVA TPFAAAMGSG QVSAYPGLQC 240
PPLPPRVGLP SQQGFSAQLV SPYPPALPQR PPPRMAPHQP GFILQ 285 |
Gene Ontology | GO:0000813; C:ESCRT I complex; ISS:UniProtKB. GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell. GO:0015031; P:protein transport; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |