UniProt Accession

 H0YBW3_HUMAN; H0YBW3 

Genbank Protein ID

 AC107964 

Genbank Nucleotide ID

  

Protein Name

 Integrator complex subunit 10 

Protein Synonyms/Alias

  

Gene Name

 INTS10 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
31	SDLMSPSKRSSQKYI	ubiquitination	[1, 2]
36	PSKRSSQKYIIEGLT	ubiquitination	[2]
190	TEVLESFKLARESWE	ubiquitination	[1]

Reference

 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 235 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IDA:HPA.
 GO:0032039; C:integrator complex; IEA:InterPro.
 GO:0005634; C:nucleus; IDA:HPA.
 GO:0016180; P:snRNA processing; IEA:InterPro. 

Interpro

 IPR026164; Int_cplx_su10. 

Pfam

  

SMART

  

PROSITE

  

PRINTS