UniProt Accession

 YPDB_ECOLI; P0AE39; P77742 

Genbank Protein ID

 U00096; AP009048 

Genbank Nucleotide ID

 AAC75440.1; BAA16251.1 

Protein Name

 Transcriptional regulatory protein YpdB 

Protein Synonyms/Alias

  

Gene Name

 ypdB 

Gene Synonyms/Alias

 b2381; JW2378 

Created Date

 July 27, 2013 

Organism

 Escherichia coli (strain K12) 

NCBI Taxa ID

 83333 

Lysine Modification

Position	Peptide	Type	References
40	DDGLDVLKFLQHNRV	acetylation	[1]
114	RITGMLQKLEAAWQQ	acetylation	[1]
143	NDTINLVKDERIIVT	acetylation	[1]
186	NITEFCSKLPPSHFF	acetylation	[1]
222	NTYILRLKDLDFEVP	acetylation	[1]

Reference

 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 

Functional Description

 Member of the two-component regulatory system YpdA/YpdB involved in carbon control network. Regulates expression of yhjX by binding to its promoter region. 

Sequence Annotation

 DOMAIN 1 116 Response regulatory.
 DOMAIN 139 244 HTH LytTR-type.
 MOD_RES 53 53 4-aspartylphosphate (Probable).  

Keyword

 Complete proteome; Cytoplasm; DNA-binding; Phosphoprotein; Reference proteome; Transcription; Transcription regulation; Two-component regulatory system. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 244 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0000156; F:phosphorelay response regulator activity; IEA:InterPro.
 GO:0035556; P:intracellular signal transduction; IEA:GOC.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 

Interpro

 IPR011006; CheY-like_superfamily.
 IPR007492; LytTR_DNA-bd_dom.
 IPR001789; Sig_transdc_resp-reg_receiver. 

Pfam

 PF04397; LytTR
 PF00072; Response_reg 

SMART

 SM00850; LytTR
 SM00448; REC 

PROSITE

 PS50930; HTH_LYTTR
 PS50110; RESPONSE_REGULATORY 

PRINTS