| Tag | Content |
|---|
| CPLM ID | CPLM-028928 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Tyrosine-protein kinase transmembrane receptor |
Protein Synonyms/Alias | |
Gene Name | ROR1 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 492 | CAFGKIYKGHLYLPG | ubiquitination | [1] | | 654 | DYYRVQSKSLLPIRW | ubiquitination | [1] |
|
Reference | [1] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C. Nat Cell Biol. 2012 Oct;14(10):1089-98. [ PMID: 23000965] |
Functional Description | |
Sequence Annotation | |
Keyword | ATP-binding; Disulfide bond; Immunoglobulin domain; Kinase; Kringle; Membrane; Nucleotide-binding; Receptor; Transferase; Transmembrane; Transmembrane helix; Tyrosine-protein kinase. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 940 AA |
Protein Sequence | RARGCSARRR GTRPPLLALL AALLLAARGA AAQETELSVS AELVPTSSWN ISSELNKDSY 60
LTLDEPMNNI TTSLGQTAEL HCKVSGNPPP TIRWFKNDAP VVQEPRRLSF RSTIYGSRLR 120
IRNLDTTDTG YFQCVATNGK EVVSSTGVLF VKFGPPPTAS PGYSDEYEED GFCQPYRGIA 180
CARFIGNRTV YMESLHMQGE IENQITAAFT MIGTSSHLSD KCSQFAIPSL CHYAFPYCDE 240
TSSVPKPRDL CRDECEILEN VLCQTEYIFA RSNPMILMRL KLPNCEDLPQ PESPEAANCI 300
RIGIPMADPI NKNHKCYNST GVDYRGTVSV TKSGRQCQPW NSQYPHTHTF TALRFPELNG 360
GHSYCRNPGN QKEAPWCFTL DENFKSDLCD IPACDSKDSK EKNKMEILYI LVPSVAIPLA 420
IALLFFFICV CRNNQKSSSA PVQRQPKHVR GQNVEMSMLN AYKPKSKAKE LPLSAVRFME 480
ELGECAFGKI YKGHLYLPGM DHAQLVAIKT LKDYNNPQQW TEFQQEASLM AELHHPNIVC 540
LLGAVTQEQP VCMLFEYINQ GDLHEFLIMR SPHSDVGCSS DEDGTVKSSL DHGDFLHIAI 600
QIAAGMEYLS SHFFVHKDLA ARNILIGEQL HVKISDLGLS REIYSADYYR VQSKSLLPIR 660
WMPPEAIMYG KFSSDSDIWS FGVVLWEIFS FGLQPYYGFS NQEVIEMVRK RQLLPCSEDC 720
PPRMYSLMTE CWNEIPSRRP RFKDIHVRLR SWEGLSSHTS STTPSGGNAT TQTTSLSASP 780
VSNLSNPRYP NYMFPSQGIT PQGQIAGFIG PPIPQNQRFI PINGYPIPPG YAAFPAAHYQ 840
PTGPPRVIQH CPPPKSRSPS SASGSTSTGH VTSLPSSGSN QEANIPLLPH MSIPNHPGGM 900
GITVFGNKSQ KPYKIDSKQA SLLGDANIHG HTESMISAEL 940 |
Gene Ontology | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0005524; F:ATP binding; IEA:UniProtKB-KW. GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; IEA:EC. GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |