CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-034599
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein Traf3 
Protein Synonyms/Alias
 Tnf receptor-associated factor 3 (Predicted) 
Gene Name
 Traf3 
Gene Synonyms/Alias
 Traf3_predicted; rCG_27660 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
368TELESVDKSAGQAARubiquitination[1]
Reference
 [1] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Metal-binding; Receptor; Reference proteome; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 567 AA 
Protein Sequence
MEPSKKMGAA GAAQPNPPLK LQPDRGAASV LVPEQGGYKE KFAKTVEDKY KCEKCRLVLC 60
NPKQTECGHR FCESCMAALL SSSSPKCTAC QESIIKDKVF KDNCCKREIL ALQIYCRNEG 120
RGCVEQLTLG HLLVHLKNEC QFEELPCLRA DCKEKVLRRD LRDHVEKACK YREATCAHCK 180
SQVPMITLQK HEDTDCPCVV VSCPHKCSVQ TLLRSELSAH LSECVNAPST CSFKRYGCVF 240
QGTNQQIKAH EASSAVQHVN LLKEWSNSLE KKVSLLQNES VEKNKSIQSL HNQICSFEIE 300
IERQKEMLRN NESKILHLQR VIDSQAEKLK ELDKEIRPFR QNWEEADSMK SSVESLQNRV 360
TELESVDKSA GQAARNTGLL ESQLSRHDQM LSVHDIRLAD MDLRFQVLET ASYNGVLIWK 420
IRDYKRRKQE AVMGKTLSLY SQPFYTGYFG YKMCARVYLN GDGMGKGTHL SLFFVIMRGE 480
YDALLPWPFK QKVTLMLMDQ GSSRRHLGDA FKPDPNSSSF KKPTGEMNIA SGCPVFVAQT 540
VLENGTYIKD DTIFIKVIVD TSDLPDP 567 
Gene Ontology
 GO:0035631; C:CD40 receptor complex; IEA:Compara.
 GO:0009898; C:internal side of plasma membrane; IEA:Compara.
 GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0045087; P:innate immune response; IEA:InterPro.
 GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IEA:Compara.
 GO:0042981; P:regulation of apoptotic process; IEA:InterPro.
 GO:0050688; P:regulation of defense response to virus; IEA:Compara.
 GO:0032648; P:regulation of interferon-beta production; IEA:Compara.
 GO:0030162; P:regulation of proteolysis; IEA:Compara.
 GO:0008063; P:Toll signaling pathway; IEA:InterPro.
 GO:0002224; P:toll-like receptor signaling pathway; IEA:Compara.
 GO:0033209; P:tumor necrosis factor-mediated signaling pathway; IEA:Compara. 
Interpro
 IPR002083; MATH.
 IPR013323; SIAH-type.
 IPR012227; TNF_rcpt--assoc_TRAF.
 IPR008974; TRAF-like.
 IPR027128; TRAF3.
 IPR001841; Znf_RING.
 IPR013083; Znf_RING/FYVE/PHD.
 IPR017907; Znf_RING_CS.
 IPR001293; Znf_TRAF. 
Pfam
 PF00917; MATH 
SMART
 SM00061; MATH
 SM00184; RING 
PROSITE
 PS50144; MATH
 PS00518; ZF_RING_1
 PS50089; ZF_RING_2
 PS50145; ZF_TRAF 
PRINTS