| Tag | Content |
|---|
| CPLM ID | CPLM-020938 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Alpha-1,3/1,6-mannosyltransferase ALG2 |
Protein Synonyms/Alias | Asparagine-linked glycosylation protein 2 homolog; GDP-Man:Man(1)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase; GDP-Man:Man(1)GlcNAc(2)-PP-dolichol mannosyltransferase; GDP-Man:Man(2)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase |
Gene Name | Alg2 |
Gene Synonyms/Alias | MNCb-5081 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 185 | QYTASVFKETFKTLS | ubiquitination | [1] | | 397 | GKARVAEKFSADAFA | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Mannosylates Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)- dolichol diphosphate (By similarity). |
Sequence Annotation | |
Keyword | Complete proteome; Glycosyltransferase; Membrane; Reference proteome; Transferase; Transmembrane; Transmembrane helix. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 415 AA |
Protein Sequence | MAENLYRARS RVYSPSVLFL HPDMGIGGAE RLVLDAALAL QEYGCDVKIW TAHYDPNHCF 60
IETRELSVQC AGDWLPRSLG WGGRGAAICS YVRMVFLALY VLFLSGEEFD VVVCDQVSAC 120
IPVFKLARRR KRVLFYCHFP DLLLTQRNSA LKKFYRAPID WIEEYTTGMA DRILVNSQYT 180
ASVFKETFKT LSHRNPDVLY PSLNIGSFDL AIPEKIDDLV PKGKQFLFLS INRYERKKNL 240
PLALRSLVQL RNRLPSQEWD KVHLFMAGGY DDRIPENVEH YKELKKMVQE SDLERHVTFL 300
RSFSDRQKIS LLHGCLCVLY TPSNEHFGIV PLEAMYMQCP VIAVNNGGPL ESIVHKVTGF 360
LCEPDPVHFS EAMEKFIHKP SLKATMGLAG KARVAEKFSA DAFADQLYQY VTKLV 415 |
Gene Ontology | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0005634; C:nucleus; IEA:Compara. GO:0048471; C:perinuclear region of cytoplasm; IEA:Compara. GO:0000033; F:alpha-1,3-mannosyltransferase activity; IEA:Compara. GO:0004378; F:GDP-Man:Man1GlcNAc2-PP-Dol alpha-1,3-mannosyltransferase activity; IEA:EC. GO:0033164; F:glycolipid 6-alpha-mannosyltransferase activity; IEA:InterPro. GO:0006488; P:dolichol-linked oligosaccharide biosynthetic process; IEA:Compara. GO:0033577; P:protein glycosylation in endoplasmic reticulum; IEA:Compara. GO:0051592; P:response to calcium ion; IEA:Compara. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |