CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-028545
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Signal recognition particle subunit SRP68 
Protein Synonyms/Alias
 SRP68 
Gene Name
 Srp68 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
103WSYAMQLKQEANTEPubiquitination[1]
238TEGLLAEKLEALITQubiquitination[1]
267RGRTVPVKIDKVRIFubiquitination[1]
465SSHGGASKNSLKDLPubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
 Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane (By similarity). 
Sequence Annotation
  
Keyword
 Complete proteome; Cytoplasm; Reference proteome; Ribonucleoprotein; RNA-binding; Signal recognition particle. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 587 AA 
Protein Sequence
MAAEKQIPGG GSGGGGSGSG GGGGGSGGGR SAGGDENKEN ERPSAGSKAN KEFGDSLSLE 60
ILQIIKESQQ QHGLRHGDFQ RYRYLLLVLM DAERAWSYAM QLKQEANTEP RKRFHLLSRL 120
RKAVKHAEEL ERLCESNRVD AKTKLEAQAY TAYLSGMLRF EHQEWKSAIE AFNKCKTIYE 180
KLASAFTEEQ AVLYNQRVEE ISPNIRYCAY NIGDQSAINE LMQMRLRSGG TEGLLAEKLE 240
ALITQTRAKQ AATMSEVEWR GRTVPVKIDK VRIFLLGLAD NEAAIVQAES EETKERLFES 300
MLSECRDALQ AVREELKPDQ KQRDYALDGE SGKVSNLQYL HSYLTYIKLS TAIRRNENMA 360
KGLHRALLQQ QPEDDSKRSP RPQDLIRLYD IILQNLVELL QLPGLEEDRT FQKEISLKTL 420
VFKAYRCFFI AQSYVLVKKW SEALVLYDRV LKYANEVSSH GGASKNSLKD LPDVQELITQ 480
VRSEKCSLQA AAILDANDSH QTDTSSQVKD NTPLVERFES FCLDPSLVTK QANLVHFPPG 540
FQPIPCKPLF FDLALNHVAF PPLEDKLEQK TKSGLTGYIK GIFGFRS 587 
Gene Ontology
 GO:0005786; C:signal recognition particle, endoplasmic reticulum targeting; IEA:UniProtKB-KW.
 GO:0008312; F:7S RNA binding; IEA:InterPro.
 GO:0030942; F:endoplasmic reticulum signal peptide binding; IEA:InterPro.
 GO:0005047; F:signal recognition particle binding; IEA:InterPro.
 GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; IEA:InterPro. 
Interpro
 IPR026258; SRP68. 
Pfam
  
SMART
  
PROSITE
  
PRINTS