| Tag | Content |
|---|
| CPLM ID | CPLM-016439 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Glutaminyl-peptide cyclotransferase-like protein |
Protein Synonyms/Alias | Golgi-resident glutaminyl-peptide cyclotransferase; isoQC; gQC |
Gene Name | Qpctl |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 81 | IGSLSEAKLRLVVGQ | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Responsible for the biosynthesis of pyroglutamyl peptides (By similarity). |
Sequence Annotation | ACT_SITE 226 226 Proton acceptor (By similarity).
ACT_SITE 270 270 Proton acceptor (By similarity).
METAL 187 187 Zinc; catalytic (By similarity).
METAL 227 227 Zinc; catalytic (By similarity).
METAL 352 352 Zinc; catalytic (By similarity). |
Keyword | Acyltransferase; Alternative splicing; Complete proteome; Golgi apparatus; Membrane; Metal-binding; Reference proteome; Transferase; Transmembrane; Transmembrane helix; Zinc. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 383 AA |
Protein Sequence | MSPGSRGRPR QRLEDRGLMK PPSLSKRRLL PRVQFLPLLL LALAMGLAFY IVWNSWHPGV 60
EEMSRSRDLR VPLIGSLSEA KLRLVVGQLD PQRLWGTFLR PLLIVRPPGS SGNLQVRKFL 120
EATLQSLSAG WHVELDPFTA STPLGPLDFG NVVATLDPGA ARHLTLACHY DSKFFPPGLP 180
PFVGATDSAV PCALLLELVQ ALDAMLSRIK QQAAPVTLQL LFLDGEEALK EWGPKDSLYG 240
SRHLAQIMES IPHSPGPTRI QAIELFVLLD LLGASSPIFF SHFPRTARWF QRLRSIEKRL 300
HRLNLLQSHP QEVMYFQPGE PPGPVEDDHI PFLRRGVPVL HLIATPFPAV WHTPADTEAN 360
LHPPTVHNLS RILAVFLAEY LGL 383 |
Gene Ontology | GO:0005794; C:Golgi apparatus; ISO:MGI. GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell. GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0016603; F:glutaminyl-peptide cyclotransferase activity; ISS:UniProtKB. GO:0008233; F:peptidase activity; IEA:InterPro. GO:0008270; F:zinc ion binding; ISS:UniProtKB. GO:0017186; P:peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase; ISS:UniProtKB. GO:0006508; P:proteolysis; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |