CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-037806
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Heat shock factor protein 1 
Protein Synonyms/Alias
  
Gene Name
 HSF1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
143RILGVKRKIPLMLNDubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; DNA-binding; Nucleus; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 430 AA 
Protein Sequence
MASFVRQLNM YGFRKVVHIE QGGLVKPERD DTEFQHPCFL RGQEQLLENI KRKVTSVSTL 60
KSEDIKIRQD SVTKLLTDVQ LMKGKQECMD SKLLAMKHEN EALWREVASL RQKHAQQQKV 120
VNKLIQFLIS LVQSNRILGV KRKIPLMLND SGSAHSMPKY SRQFSLEHVH GSGPYSAPSP 180
AYSSSSLYAP DAVASSGPII SDITELAPAS PMASPGGSID ERPLSSSPLV RVKEEPPSPP 240
QSPRVEEASP GRPSSVDTLL SPTALIDSIL RESEPAPASV TALTDARGHT DTEGRPPSPP 300
PTSTPEKCLS VACLDNLART PQMSRVARLF PCPSSSPHGQ VQPGNELSDH LDAMDSNLDN 360
LQTMLSSHGF SVDTSALLDI QELLSPQEPP RPPEAENSSP DSAGALHSAA AVPAGPRLRG 420
HREQRPAGAV 430 
Gene Ontology
 GO:0005634; C:nucleus; IEA:UniProtKB-KW.
 GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
 GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
 GO:0009408; P:response to heat; IEA:InterPro.
 GO:0006351; P:transcription, DNA-dependent; IEA:InterPro. 
Interpro
 IPR027072; HSF1.
 IPR000232; HSF_DNA-bd.
 IPR010542; Vert_HS_TF.
 IPR011991; WHTH_DNA-bd_dom. 
Pfam
 PF00447; HSF_DNA-bind
 PF06546; Vert_HS_TF 
SMART
 SM00415; HSF 
PROSITE
  
PRINTS