CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038617
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Centrosomal protein of 290 kDa 
Protein Synonyms/Alias
  
Gene Name
 Cep290 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
2175EEENRNLKAELEKLKacetylation[1]
2180NLKAELEKLKAHFGRacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 2479 AA 
Protein Sequence
MPPNIKWKEL IKVDPDDLPR QEELADKLLI SLSKVEVNEL KNEDQENMIH LFRITQSLMK 60
MKAQEVELAL EEVEKAGEEQ AKFENQLKTK VMKLENELEM AQQSAGGRDT RFLRDEIRQL 120
EKQLEQKDRE LEDMEKELDK EKKVNEQLAL RNEEAENENS KLRRENKRLK KKNEQLRQDI 180
IDYQKQIDSQ KESLLSRRGE DSDYRSQLSK KNYELVQYLD EIQTLTEANE KIEVQNQEMR 240
KNLEESVQEM EKMTDEYNRM KALVHQSDAV MDQIKKENEH YRLQVRELTD LLKAKDEEDD 300
PVMMAVNAKV EEWKLILSSK DDEIIEYQQM LQSLRGKLKN AQLDADKSNI MALKQGIQER 360
DSQIKMLTEQ VEQYTKEMEK NTFIIEDLKN ELQKDKGTSN FYQQTHYMKI HSKVQILEEK 420
TKEAERIAEL AEADAREKDK ELVEALKRLK DYESGVYGLE DAVIEIKNCK AQIKIRDGEM 480
EVLTKEINKL EMKINDILDE NEALRERAGL EPKTMIDLTE FRNSKRLKQQ QYRAENQVLL 540
KEIESLEEER LDLKRKIRQM AQERGKRNAA SGLTIDDLNL SETFSHENKI EGRKLNFMSL 600
NNMNETQSKN EFLSRELAEK EKDLERSRTV IAKFQSKLKE LVEENKQLEE GMKEILQAIK 660
DMPKDSDVKG GETSLIIPSL ERLVNAMESK NAEGIFDASL HLKAQVDQLT GRNEELRQEL 720
RQSRKEAVNY SQQLVKANLK IDHLEKETDL LRQSAGSNVV YKGIDLPDGI APSSAYIINS 780
QNEYLIHLLQ ELDNKEKKLK HLEDSLEDYN RKFAVIRHQQ SLLYKEYLSE KDIWKTDSEM 840
IREEKRKLED QAEQDAVKVK EYNNLLSALQ MDSNEMKKML SENSRKITVL QVNEKSLIRQ 900
YTTLVEMERH LRKENGKHRN DVIAMEAEVT EKLGSLQRFK EMAIFKIAAL QKVIDNSVSL 960
SELELANKQY NELTTKYRDI LQKDNMLVQR TSNLEHLECE NASLKEQMEA ISKELEITKE 1020
KLHTIEQAWE QETKLGNDSN MDKAKKSMTN SDIVSISKKI TVLEMKELNE RQRAEHCQKM 1080
YEHLRTSLKQ MEERNFELET KFTELTKINL DAQKVEQMLR DELADSVTKA VSDADRQRIL 1140
ELEKSEVELK VEVSKLREIS DIAKRQVDFL NSQQQSREKE VESLRTQLLD FQAQSDEKAL 1200
IAKLHQHVVS LQISEATALG KLESVTSKLQ KMEAYNLRLE QKLDEKEQAL YYARLEGRNR 1260
AKHLRQTIQS LRRQFSGALP LAQQEKFSKT MIQLQNDKLK IMQEMKNSQQ EHRNMENKTL 1320
ELELKLKGLE ELISTLKDAR GAQKVINWHV KIEELRLQEL KLNRELVKGK EEIKYLNNII 1380
SEYEHTINSL EEEIVQQSKF HEERQMAWDQ REVELERQLD IFDHQQNEIL SAAQKFEDST 1440
GSMPDPSLPL PNQLEIALRK IKENIQVILK TQATCKSLEE KLKEKESALR LAEQNILSRD 1500
KVINELRLRL PATADREKLI AELERKELEP KSHHTMKIAH QTIANMQARL NHKEEVLKKY 1560
QHLLEKAREE QREIVKKHEE DLHVLHHKLE QQADNSLNKF RQTAQDLLKQ SPAPVPTNKH 1620
FIRLAEMEQT VAEQDDSLSS LLTKLKKVSK DLEKQKEITE LKVREFENTK LRLQETHASE 1680
VKKVKAEVED LRHALAQAHK DSQSLKSELQ AQKEANSRAP TTTMRNLVDR LKSQLALKEK 1740
QQKALSRALL ELRSEMTAAA EERIIAVTSQ KEANLNVQQV VERHTRELKS QIEDLNENLL 1800
KLKEALKTSK NKENSLADDL NELNNELQKK QKAYNKILRE KDGIDQENDE LRRQIKRLSS 1860
GLQSKTLIDN KQSLIDELQK KVKKLESQLE RKVDDVDIKP VKEKSSKEEL IRWEEGKKWQ 1920
TKVEGLRNRL KEKEGEAHGL AKQLNTLKEL FAKADKEKLT LQKKLKTTGM TVDQVLGVRA 1980
LESEKELEEL KKKNLDLEND ILYMRTQQAL PRDSVVEDLH LQNKYLQEKL HTLEKKLSKE 2040
KYSQSLTSEI ESDDHCQKEQ ELQKENLKLS SENIELKFQL EQANKDLPRL KNQVKDLKEM 2100
CEFLKKGKLE LERKLGQVRG AGRSGKTIPE LEKTIGLMKK VVEKVQRENE QLKKASGILT 2160
SEKMATIEEE NRNLKAELEK LKAHFGRQLS MQFESKNKGT EKIVAENERL RKELKKEIEA 2220
SEKLRIAKNN LELVNDKMAA QLEETGKRLQ FAESRAPQLE GADSKSWKSI VVSRVYETKM 2280
KELESDIAKK NQSITDLKQL VREATEREQK AKKYTEDLEQ QIEILKNVPE GAETEQELIR 2340
ELQLLRLANN QMDKERAELI HQIEINKDQT RADSSIPDSD QLKEKINDLE TQLRKLELEK 2400
QHSKEEVKKL KKELENFDPS FFEEIEDLKY NYKEEVKKNI LLEEKLKKLS EQFGFELPSP 2460
LAASEHSEDG ESPHSFPIY 2479 
Gene Ontology
 GO:0009986; C:cell surface; IEA:Compara.
 GO:0005813; C:centrosome; IEA:Compara.
 GO:0005829; C:cytosol; IEA:Compara.
 GO:0000930; C:gamma-tubulin complex; IEA:Compara.
 GO:0005634; C:nucleus; IEA:Compara.
 GO:0060271; P:cilium morphogenesis; IMP:MGI.
 GO:0007163; P:establishment or maintenance of cell polarity; IMP:MGI.
 GO:0045893; P:positive regulation of transcription, DNA-dependent; IEA:Compara.
 GO:0030814; P:regulation of cAMP metabolic process; IMP:MGI.
 GO:0060041; P:retina development in camera-type eye; IMP:MGI. 
Interpro
 IPR026201; Cep290. 
Pfam
  
SMART
  
PROSITE
  
PRINTS