UniProt Accession

 DHAL_ECOLI; P76014 

Genbank Protein ID

 U00096; AP009048 

Genbank Nucleotide ID

 AAC74283.1; BAA36056.2 

Protein Name

 PTS-dependent dihydroxyacetone kinase, ADP-binding subunit DhaL 

Protein Synonyms/Alias

  

Gene Name

 dhaL 

Gene Synonyms/Alias

 ycgS; b1199; JW5186 

Created Date

 July 27, 2013 

Organism

 Escherichia coli (strain K12) 

NCBI Taxa ID

 83333 

Lysine Modification

Position	Peptide	Type	References
48	NMNRGFSKVVEKLPA	acetylation	[1]
52	GFSKVVEKLPAIADK	acetylation	[1]
59	KLPAIADKDIGFILK	acetylation	[1]

Reference

 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 

Functional Description

 ADP-binding subunit of the dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone. DhaL- ADP receives a phosphoryl group from DhaM and transmits it to dihydroxyacetone. DhaL-ADP acts also as a coactivator by binding to the sensor domain of DhaR. DhaL-ATP is inactive. 

Sequence Annotation

 DOMAIN 6 206 DhaL.
 NP_BIND 35 41 ADP.
 NP_BIND 79 80 ADP.
 NP_BIND 191 193 ADP.
 BINDING 121 121 ADP; via carbonyl oxygen.
 BINDING 178 178 ADP.  

Keyword

 3D-structure; ATP-binding; Complete proteome; Glycerol metabolism; Kinase; Nucleotide-binding; Reference proteome; Transferase. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 210 AA 

Protein Sequence

Gene Ontology

 GO:0043531; F:ADP binding; IDA:EcoCyc.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0004371; F:glycerone kinase activity; IPI:EcoliWiki.
 GO:0000287; F:magnesium ion binding; IDA:EcoCyc.
 GO:0019563; P:glycerol catabolic process; IEA:UniProtKB-UniPathway. 

Interpro

 IPR004007; Dak2.
 IPR012737; DhaK_L_YcgS. 

Pfam

 PF02734; Dak2 

SMART

  

PROSITE

 PS51480; DHAL 

PRINTS