CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-016675
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX32 
Protein Synonyms/Alias
 DEAH box protein 32; MuDDX32 
Gene Name
 Dhx32 
Gene Synonyms/Alias
 Ddx32 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
397QSQAEIRKQLLGSSPubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
  
Sequence Annotation
 DOMAIN 72 270 Helicase ATP-binding.
 DOMAIN 258 438 Helicase C-terminal.
 NP_BIND 85 92 ATP (By similarity).
 MOTIF 185 188 DEAH box.  
Keyword
 Alternative splicing; ATP-binding; Complete proteome; Helicase; Hydrolase; Mitochondrion; Nucleotide-binding; Nucleus; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 744 AA 
Protein Sequence
MSSLREEMDE EELDHPNASP EKRYFPESLD SSDGDEEGVL ACEDLELNPF DGLPYSSRYY 60
KLLKEREELP IWKEKYSFME SLLQNQVVVV SGDSKCGKSS QVPQWCAEYC LSIHYQHGGV 120
ICTQAHKQTA VQLALRVADE MDVNIGHEVG YVIPFENCCT TETILRYCTD DMLQREMMSN 180
PFLGSYGVII LDDVHERSLA TDVLLGLLKD VLLARPELKL IVNCSPLLTS KLSSYYGDVP 240
VIEVRNKHPV EVVYLSGAQK DSFESVIRLI FEIHRSGEKG DVVVFLACEQ DIEKTYELVC 300
QEGSNLNPDV GDLVVIPLYP KEKCSLFRPV DETEKRCQVY QRRVVLTTSC GESLIWSHTV 360
KFVIDVGLER RQVYNPRIRA NSLVLQPISQ SQAEIRKQLL GSSPSGKLFC LYTEEFASKD 420
MRPLKPAEMQ EANLTSMVLF MKRVDIAGLG RCDFMNRPAP ESLMQALEDL DYLAALDNDG 480
NLSEFGIIMS EFPLDPQLSK SILASCEFDC VDEMLTIAAM VTAPSCFLHV PHGAEEAAVT 540
CWKTFLHPEG DHFTLINVYN AYQDTVLNSA NEHCVEMWCH DCFLSCSALR MADVIRAELL 600
EIIKRIELPY AEPAFGSKEN GLNIKKALLS GYFMQIARDV DGSGNYLMLT HKQVAQLHPL 660
SSYSITKKMP EWVLFHQFSI SENNYIRVAS AVSPELFMQL VPQYYFSNLP PSESKDILQQ 720
AAGHLPTETV NKDQDVCDKC PDATEQRCTI Q 751 
Gene Ontology
 GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0004386; F:helicase activity; IEA:UniProtKB-KW. 
Interpro
 IPR011709; DUF1605.
 IPR007502; Helicase-assoc_dom.
 IPR027417; P-loop_NTPase. 
Pfam
 PF04408; HA2
 PF07717; OB_NTP_bind 
SMART
 SM00847; HA2 
PROSITE
 PS51192; HELICASE_ATP_BIND_1
 PS51194; HELICASE_CTER 
PRINTS