UniProt Accession

 E9PM14_HUMAN; E9PM14 

Genbank Protein ID

 AP003032 

Genbank Nucleotide ID

  

Protein Name

 NADH dehydrogenase [ubiquinone] 1 subunit C2 

Protein Synonyms/Alias

  

Gene Name

 NDUFC2 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
94	REMFGYMKLHPEDFP	ubiquitination	[1]

Reference

 [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661] 

Functional Description

 Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). 

Sequence Annotation

  

Keyword

 Complete proteome; Electron transport; Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome; Respiratory chain; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 107 AA 

Protein Sequence

Gene Ontology

 GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
 GO:0070469; C:respiratory chain; IEA:UniProtKB-KW.
 GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:InterPro.
 GO:0006120; P:mitochondrial electron transport, NADH to ubiquinone; IEA:InterPro. 

Interpro

 IPR009423; NADH-UbQ_OxRdtase_b14.5b_su. 

Pfam

 PF06374; NDUF_C2 

SMART

  

PROSITE

  

PRINTS