UniProt Accession

 D3Z8V4_RAT; D3Z8V4 

Genbank Protein ID

 AABR06052804; AABR06052805; CH474035 

Genbank Nucleotide ID

 EDL86781.1 

Protein Name

 NCK associated protein 1 like (Predicted) 

Protein Synonyms/Alias

 Protein Nckap1l 

Gene Name

 Nckap1l 

Gene Synonyms/Alias

 Nckap1l_predicted; rCG_50580 

Created Date

 July 27, 2013 

Organism

 Rattus norvegicus (Rat) 

NCBI Taxa ID

 10116 

Lysine Modification

Position	Peptide	Type	References
14	YQHKLAEKLTILNDR	ubiquitination	[1]
313	EDLFSSLKGYSKRVA	acetylation	[2]

Reference

 [1] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113]
 [2] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 1106 AA 

Protein Sequence

Gene Ontology

 GO:0005829; C:cytosol; IEA:Compara.
 GO:0031209; C:SCAR complex; IEA:Compara.
 GO:0030295; F:protein kinase activator activity; IEA:Compara.
 GO:0030675; F:Rac GTPase activator activity; IEA:Compara.
 GO:0070358; P:actin polymerization-dependent cell motility; IEA:Compara.
 GO:0001782; P:B cell homeostasis; IEA:Compara.
 GO:0050853; P:B cell receptor signaling pathway; IEA:Compara.
 GO:0030866; P:cortical actin cytoskeleton organization; IEA:Compara.
 GO:0048821; P:erythrocyte development; IEA:Compara.
 GO:0030011; P:maintenance of cell polarity; IEA:Compara.
 GO:0043066; P:negative regulation of apoptotic process; IEA:Compara.
 GO:0032700; P:negative regulation of interleukin-17 production; IEA:Compara.
 GO:0032715; P:negative regulation of interleukin-6 production; IEA:Compara.
 GO:0035509; P:negative regulation of myosin-light-chain-phosphatase activity; IEA:Compara.
 GO:0030593; P:neutrophil chemotaxis; IEA:Compara.
 GO:0030838; P:positive regulation of actin filament polymerization; IEA:Compara.
 GO:0045579; P:positive regulation of B cell differentiation; IEA:Compara.
 GO:0030890; P:positive regulation of B cell proliferation; IEA:Compara.
 GO:0043372; P:positive regulation of CD4-positive, alpha-beta T cell differentiation; IEA:Compara.
 GO:0043378; P:positive regulation of CD8-positive, alpha-beta T cell differentiation; IEA:Compara.
 GO:0033630; P:positive regulation of cell adhesion mediated by integrin; IEA:Compara.
 GO:0045648; P:positive regulation of erythrocyte differentiation; IEA:Compara.
 GO:0045588; P:positive regulation of gamma-delta T cell differentiation; IEA:Compara.
 GO:0090023; P:positive regulation of neutrophil chemotaxis; IEA:Compara.
 GO:0060100; P:positive regulation of phagocytosis, engulfment; IEA:Compara.
 GO:0042102; P:positive regulation of T cell proliferation; IEA:Compara.
 GO:0006461; P:protein complex assembly; IEA:Compara.
 GO:0042493; P:response to drug; IEA:Compara.
 GO:0043029; P:T cell homeostasis; IEA:Compara. 

Interpro

 IPR019137; Nck-associated_protein-1. 

Pfam

 PF09735; Nckap1 

SMART

  

PROSITE

  

PRINTS