UniProt Accession

 Z780A_HUMAN; O75290; E9PB48; Q6ZN87 

Genbank Protein ID

 AK091274; AK131328; AC005614 

Genbank Nucleotide ID

 BAD18488.1; AAC34327.1 

Protein Name

 Zinc finger protein 780A 

Protein Synonyms/Alias

  

Gene Name

 ZNF780A 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
521	LQLSQHQKTHTGEKP	methylation	[1]
527	QKTHTGEKPFECKEC	methylation	[1]
583	QKLHTGEKPFECKEC	ubiquitination	[2]
588	GEKPFECKECGKAFR	ubiquitination	[2]

Reference

 [1] Large-scale global identification of protein lysine methylation in vivo.
 Cao XJ, Arnaudo AM, Garcia BA.
 Epigenetics. 2013 May 1;8(5):477-85. [PMID: 23644510]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

 May be involved in transcriptional regulation (By similarity). 

Sequence Annotation

 DOMAIN 6 77 KRAB.
 ZN_FING 165 187 C2H2-type 1.
 ZN_FING 193 215 C2H2-type 2.
 ZN_FING 221 243 C2H2-type 3.
 ZN_FING 249 271 C2H2-type 4.
 ZN_FING 277 299 C2H2-type 5.
 ZN_FING 305 327 C2H2-type 6.
 ZN_FING 333 355 C2H2-type 7.
 ZN_FING 361 383 C2H2-type 8.
 ZN_FING 389 411 C2H2-type 9.
 ZN_FING 417 439 C2H2-type 10.
 ZN_FING 445 467 C2H2-type 11.
 ZN_FING 473 495 C2H2-type 12.
 ZN_FING 501 523 C2H2-type 13.
 ZN_FING 529 551 C2H2-type 14.
 ZN_FING 557 579 C2H2-type 15.
 ZN_FING 585 607 C2H2-type 16.
 ZN_FING 613 635 C2H2-type 17.  

Keyword

 Alternative splicing; Complete proteome; DNA-binding; Metal-binding; Nucleus; Reference proteome; Repeat; Transcription; Transcription regulation; Zinc; Zinc-finger. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 641 AA 

Protein Sequence

Gene Ontology

 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 

Interpro

 IPR001909; Krueppel-associated_box.
 IPR007087; Znf_C2H2.
 IPR015880; Znf_C2H2-like.
 IPR013087; Znf_C2H2/integrase_DNA-bd. 

Pfam

 PF01352; KRAB 

SMART

 SM00349; KRAB
 SM00355; ZnF_C2H2 

PROSITE

 PS50805; KRAB
 PS00028; ZINC_FINGER_C2H2_1
 PS50157; ZINC_FINGER_C2H2_2 

PRINTS