| Tag | Content |
|---|
| CPLM ID | CPLM-002669 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | UDP-glucuronosyltransferase 2B17 |
Protein Synonyms/Alias | UDPGT 2B17; 17-beta-hydroxysteroid-specific UDPGT; RLUG38; Testosterone, dihydrotestosterone, and beta-estradiol-specific UDPGT; UDP-glucuronosyltransferase 2B5; UDPGT 2B5; UDPGTr-3 |
Gene Name | Ugt2b17 |
Gene Synonyms/Alias | Ugt2b3; Ugt2b5 |
Created Date | July 27, 2013 |
Organism | Rattus norvegicus (Rat) |
NCBI Taxa ID | 10116 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 456 | IHHDQPMKPLDKAVF | acetylation | [1] |
|
Reference | [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns. Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV. Cell Rep. 2012 Aug 30;2(2):419-31. [ PMID: 22902405] |
Functional Description | UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. 2B17 is active on testosterone. |
Sequence Annotation | |
Keyword | 3D-structure; Complete proteome; Endoplasmic reticulum; Glycosyltransferase; Membrane; Microsome; Reference proteome; Signal; Transferase; Transmembrane; Transmembrane helix. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 530 AA |
Protein Sequence | MPGKWISALL LLQISCCFQS GNCGKVLVWP MEFSHWMNIK TILDELVQRG HEVTVLKPSA 60
YYVLDPKKSP DLKFETFPTS VSKDELENYF IKLVDVWTYE LQRDTCLSYS PLLQNMIDGF 120
SDYYLSLCKD TVSNKQLMAK LQESKFDVLL SDPVAACGEL IAEVLHIPFL YSLRFSPGYK 180
IEKSSGRFIL PPSYVPVILS GMGGPMTFID RVKNMICTLY FDFWFHMFNA KKWDPFYSEI 240
LGRPTTLAET MGKAEMWLIR SYWDLEFPHP TLPNVDYIGG LQCRPPKPLP KDMEDFVQSS 300
GEHGVVVFSL GSMVSSMTEE KANAIAWALA QIPQKVLWKF DGKTPATLGP NTRVYKWLPQ 360
NDLLGHPKTK AFVTHSGANG VYEAIYHGIP MVGIPMFGEQ HDNIAHMVAK GAAVTLNIRT 420
MSKSDLFNAL KEIINNPFYK KNAVWLSTIH HDQPMKPLDK AVFWIEFVMR HKGAKHLRPL 480
GHDLPWYQYH SLDVIGFLLT CSAVIAVLTV KCFLFIYRLF VKKEKKMKNE 530 |
Gene Ontology | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell. GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0015020; F:glucuronosyltransferase activity; IDA:RGD. GO:0071361; P:cellular response to ethanol; IEP:RGD. GO:0071385; P:cellular response to glucocorticoid stimulus; IEP:RGD. GO:0071378; P:cellular response to growth hormone stimulus; IEP:RGD. GO:0071394; P:cellular response to testosterone stimulus; IEP:RGD. GO:0032496; P:response to lipopolysaccharide; IEP:RGD. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |