UniProt Accession

 CISD2_DROME; Q9VAM6 

Genbank Protein ID

 AE014297; AY071722; AY095084 

Genbank Nucleotide ID

 AAF56878.1; AAL49344.1; AAM11412.1 

Protein Name

 CDGSH iron-sulfur domain-containing protein 2 homolog 

Protein Synonyms/Alias

  

Gene Name

 CG1458 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Drosophila melanogaster (Fruit fly) 

NCBI Taxa ID

 7227 

Lysine Modification

Position	Peptide	Type	References
83	HIRKNEPKVVDMIDV	acetylation	[1]
132	NVGPIVIKK******	acetylation	[1]

Reference

 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702] 

Functional Description

  

Sequence Annotation

 METAL 100 100 Iron-sulfur (2Fe-2S) (By similarity).
 METAL 102 102 Iron-sulfur (2Fe-2S) (By similarity).
 METAL 111 111 Iron-sulfur (2Fe-2S) (By similarity).
 METAL 115 115 Iron-sulfur (2Fe-2S); via pros nitrogen  

Keyword

 2Fe-2S; Complete proteome; Endoplasmic reticulum; Iron; Iron-sulfur; Membrane; Metal-binding; Reference proteome; Transmembrane; Transmembrane helix. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 133 AA 

Protein Sequence

Gene Ontology

 GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.
 GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. 

Interpro

 IPR018967; FeS-contain_CDGSH-typ.
 IPR006622; FeS-contain_CDGSH-typ_subfam.
 IPR019610; FeS-contain_mitoNEET_N. 

Pfam

 PF10660; MitoNEET_N
 PF09360; zf-CDGSH 

SMART

 SM00704; ZnF_CDGSH 

PROSITE

  

PRINTS