CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-003102
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Phosphatidylserine decarboxylase proenzyme 
Protein Synonyms/Alias
 Phosphatidylserine decarboxylase alpha chain; Phosphatidylserine decarboxylase beta chain 
Gene Name
 psd 
Gene Synonyms/Alias
 b4160; JW4121 
Created Date
 July 27, 2013 
Organism
 Escherichia coli (strain K12) 
NCBI Taxa ID
 83333 
Lysine Modification
Position
Peptide
Type
References
15SLQYILPKLWLTRLAacetylation[1]
50KYYKVDMKEAQKPDTacetylation[1]
54VDMKEAQKPDTASYRacetylation[1]
103LGKIEEDKILQAKGHacetylation[1]
318ASPLVDDKKDQV***acetylation[1]
319SPLVDDKKDQV****acetylation[1]
Reference
 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 
Functional Description
  
Sequence Annotation
 MOD_RES 1 1 N-formylmethionine.
 MOD_RES 254 254 Pyruvic acid (Ser).  
Keyword
 Cell membrane; Complete proteome; Decarboxylase; Direct protein sequencing; Formylation; Lipid biosynthesis; Lipid metabolism; Lyase; Membrane; Phospholipid biosynthesis; Phospholipid metabolism; Pyruvate; Reference proteome; Zymogen. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 322 AA 
Protein Sequence
MLNSFKLSLQ YILPKLWLTR LAGWGASKRA GWLTKLVIDL FVKYYKVDMK EAQKPDTASY 60
RTFNEFFVRP LRDEVRPIDT DPNVLVMPAD GVISQLGKIE EDKILQAKGH NYSLEALLAG 120
NYLMADLFRN GTFVTTYLSP RDYHRVHMPC NGILREMIYV PGDLFSVNHL TAQNVPNLFA 180
RNERVICLFD TEFGPMAQIL VGATIVGSIE TVWAGTITPP REGIIKRWTW PAGENDGSVA 240
LLKGQEMGRF KLGSTVINLF APGKVNLVEQ LESLSVTKIG QPLAVSTETF VTPDAEPAPL 300
PAEEIEAEHD ASPLVDDKKD QV 322 
Gene Ontology
 GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
 GO:0004609; F:phosphatidylserine decarboxylase activity; IDA:EcoCyc.
 GO:0006646; P:phosphatidylethanolamine biosynthetic process; IEA:UniProtKB-UniPathway.
 GO:0008654; P:phospholipid biosynthetic process; IDA:EcoCyc. 
Interpro
 IPR003817; PS_Dcarbxylase.
 IPR005221; PS_decarb. 
Pfam
 PF02666; PS_Dcarbxylase 
SMART
  
PROSITE
  
PRINTS