CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-035480
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Jumonji domain containing 2A (Predicted) 
Protein Synonyms/Alias
 Protein Kdm4a 
Gene Name
 Kdm4a 
Gene Synonyms/Alias
 Jmjd2a_predicted; rCG_50367 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
413RLVFSGSKKKASSSLacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Metal-binding; Nucleus; Reference proteome; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 971 AA 
Protein Sequence
MTVREFRKIA NSDKYCTPRY SEFEELERKY WKNLTFNPPI YGADVNGTLY EQHVDEWNIG 60
RLKTILDLVE KESGITIEGV NTPYLYFGMW KTSFAWHTED MDLYSINYLH FGEPKSWYSV 120
PPEHGKRLER LAKGFFPGSA QSCEAFLRHK MTLISPLMLK KYGIPFDKVT QEAGEFMITF 180
PYGYHAGFNH GFNCAESTNF ATRRWIEYGK QAVLCSCRKD MVKISMDVFV RRFQPERYKL 240
WKAGKDSTVI DHTLPTPEAA EFLKDSGLTP RAGNEECPEE DSEAAEQGEE GDVKRSLAKH 300
RIGTKRHRVC LEIPQEVSQS ELFPKEELSS GQYEMTECQA TLAPVRPTHS SVRQVEDSLP 360
FPDYSDPTEV KFEELKNVKL EEEDEDEEPE AAALDLSVNP ESVEGRLVFS GSKKKASSSL 420
GSSSSQDSVS SDSETTESVS CQGQEKTVLT VHSYSRGDGK AAPGEPSVKR QRSAPRSISE 480
QELAEVADEY MLSLEENKKT KGRRQPLSKL PRHHPLVLQE CGSDDETSEQ LTPEEEAEET 540
EAWAKPLSQL WQNRPPNFEA EKEFNELMAQ QAPHCAVCMI FQTYHQVEFG GFSQSCGNAS 600
EPAAQPQRTK PLIPEMCFTT TGCSTDINLS TPYLEEDGTS MLVSCKKCSV RVHASCYGVP 660
PAKASEEWMC SRCSANALEE DCCLCSLRGG ALQRANDDRW VHVSCAVAIL EARFVNIAER 720
SPVDVSKIPL PRFKLKCVFC KKRRKRNAGC CVQCSHGRCP TAFHVSCAQA AGVMMQPDDW 780
PFVVFITCFR HKIPNLERAK GALLSITAGQ KVISKHKNGR FYQCEVVRLT TETFYEVNFD 840
DGSFSDNLYP EDIVSQDCLQ LGPPAEGEVV QVRWTDGQVY GAKFVASHPI QMYQVEFEDG 900
SQLVVKRDDV YTLDEELPKR VKSRLSVASD MRFNEIFTEK EVKQEKKRQR VINSRYREDY 960
IEPALYRAIM E 971 
Gene Ontology
 GO:0005813; C:centrosome; IEA:Compara.
 GO:0005737; C:cytoplasm; IEA:Compara.
 GO:0005730; C:nucleolus; IEA:Compara.
 GO:0051864; F:histone demethylase activity (H3-K36 specific); IEA:Compara.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0045892; P:negative regulation of transcription, DNA-dependent; IEA:Compara. 
Interpro
 IPR003347; JmjC_dom.
 IPR002999; Tudor.
 IPR011011; Znf_FYVE_PHD.
 IPR001965; Znf_PHD.
 IPR013083; Znf_RING/FYVE/PHD. 
Pfam
 PF02373; JmjC 
SMART
 SM00558; JmjC
 SM00249; PHD
 SM00333; TUDOR 
PROSITE
 PS51184; JMJC 
PRINTS