CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-033242
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Synaptosomal-associated protein 
Protein Synonyms/Alias
  
Gene Name
 SNAP29 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
14QDLKISQKHINSIKSubiquitination[1, 2]
31GGLVNYFKSKPVETPubiquitination[1]
33LVNYFKSKPVETPPEubiquitination[1, 2, 3, 4]
61KEAISTSKEQEAKYQubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [3] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [4] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661
Functional Description
  
Sequence Annotation
  
Keyword
 Cell junction; Complete proteome; Reference proteome; Synapse; Synaptosome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 160 AA 
Protein Sequence
MVDKMDQDLK ISQKHINSIK SVFGGLVNYF KSKPVETPPE QNGTLTSQPN NRLKEAISTS 60
KEQEAKYQAS HPNLRKLDDT DPVPRGAGSA MSTDAYPKNP HLRAYHQKID SNLDELSMGL 120
GRLKDIALGM QTEIEEQDDI LDRLTTKVDK LDVNIKSTER 160 
Gene Ontology
 GO:0005737; C:cytoplasm; IDA:HPA.
 GO:0043005; C:neuron projection; IEA:UniProtKB-KW.
 GO:0005634; C:nucleus; IDA:HPA. 
Interpro
 IPR000928; SNAP-25.
 IPR000727; T_SNARE_dom. 
Pfam
 PF00835; SNAP-25
 PF05739; SNARE 
SMART
 SM00397; t_SNARE 
PROSITE
 PS50192; T_SNARE 
PRINTS