CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027309
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Serine/threonine kinase 
Protein Synonyms/Alias
  
Gene Name
 LA_1164 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Leptospira interrogans serogroup Icterohaemorrhagiae serovar La 
NCBI Taxa ID
 189518 
Lysine Modification
Position
Peptide
Type
References
903GRSPERLKEAKKNQDmethylation[1]
Reference
 [1] High-coverage proteome analysis reveals the first insight of protein modification systems in the pathogenic spirochete Leptospira interrogans.
 Cao XJ, Dai J, Xu H, Nie S, Chang X, Hu BY, Sheng QH, Wang LS, Ning ZB, Li YX, Guo XK, Zhao GP, Zeng R.
 Cell Res. 2010 Feb;20(2):197-210. [PMID: 19918266] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Kinase; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1759 AA 
Protein Sequence
MSIRTETSFH KKEILLEDHV STIYRGILKG ESETKILRIQ KERTRDEDSF YFLNEYEIGK 60
LISDDHILKP ERLIKIQDRY CLIYENLESS LLSNYISKVG QLSIEEFLQV AISITGNLVH 120
LHSQGVLHNQ IGPSSFFYDT DTKTSVLAWL GSSSLLLGEK GNLAPLQISP TLLAYCSPER 180
TGRLNRSVDF RSDGYSIGIL FYQFLTGKPP FESDDPLEII HAHVARVPVA ISEKRKEIPI 240
PISSLVMKLL SKMPEERYFS LETLLHDLRM LNDSIRSRKS VLEFIPGFTE KKDKFRISEK 300
LYGREKEKEI IEEAISAVYS GVKAAILIKG KSGTGKTSLI QDTILSKELN TLRSFKGKFE 360
EDKKEIPYFA LRQILVELCN HLLTQSEYEI RSFRREIREK LGDNIHLLTQ FIPEIVNLLE 420
VHSVSSDYQS QKDDQFLFVV ILRFLSSCFN RHNPALLILD DVQWADSASL SLIEFISRQT 480
EWEGMLFVFI CRNEEEHSDF LNSFRERILN SEILLQEISL NPLDPMMIRN YVTDSLDLQE 540
EDTKKLTEIL YQKTNGNPFF LNQFFNNLYT ESYIQYQKSS GIWSLDWDQI IKKTVTENVL 600
DLLTEEITRL PENTQKLLKV AACVGNLFDL GILYRYFQNS PEIIETGIRE CIKQGIVIYQ 660
ESQVSLYPVL QILKKENAEG LDKNKLFEGI MFRFSHDKIN QVIVESIFSE QRAEIHKNLA 720
WFLVESDLVS SKQERIQEIA NHLVKSQKII NSKEDLEVFN RYLVLAGNLA KLSAAFNTAY 780
NLFSLLKKKI TEESWTERKD QCIQIYKSFA ESAYFLSKTF EAEDTVQVLL SKLHDRIEIA 840
DVYLMQLEVM NAKNDLDGAY KVGLKALKSL NVQFPEKPGI WILTLEFLKM IYYQRGRSPE 900
RLKEAKKNQD PYKIETINIL TNMLNYGKHS DSKLFVFLFL KLMNITLKEG NSPVSFFGYA 960
GFGSLLFAMT GNLHTALRYW DLGEYVIQIF NADRVKGRYL FGKNMLLDFY RVPFSKLALF 1020
SEEAYEKCIQ YGDYLWAAFS LIAHSIYQFY SSDNAESYYE ILIKDVKRAE QLGYETVYVI 1080
AASSDFLIRS LGNPFRPNVI YKDREMSVET FEREILIPNA NGTANTWYAV LRGKETYLRG 1140
EWEEGLKIFS QFANDLERSR TIFIYSEYRF FKSLHLIRLN EVGKKISFSD LYFIKRSISL 1200
FKTWSETFPD NFKSYWYILK AEYNKYKKNF TKAEIFFELA LFSLQKNDNN LRKAIVYEHA 1260
GMWEFGRGRK QYSNYLLKIA EKQYRTWGAS AKANRIQTIR QPDEDAGIFL HTREEALLDT 1320
ILKSAENLDL RSVLKSSQSI SESIEQDELL KKLMRTIMEN AGATRGFLIL PRKSGFYVET 1380
GQDIEDENIL PKSLILDSAS ELLPVEIVYY CYRSGQKILL NNTSSKDSLH SLNPYVIEKQ 1440
PKSLLCFPIT KQGKILSVLY LENRLTYDVF DEHRLEILEI LSSQAAISLE NAKLYEDITS 1500
LNAELEKKVE LRTQELMQSL KIIRKDLLYS KKIQRSILPD HPNLPGILYA VSYQPMDEVG 1560
GDFYDLFEIR PGVYRFFVAD ATGHGVQAAL ITMAIKSEYE HLKKTEKNPS NILKELNVVI 1620
LEKFKTLYLT CVVADINVND YTLEYSSAGH PPQVLWRDGK ADFLHKTGAI LGLKKDFIYY 1680
SENVELKPED RIFLFTDGVY EQFNSNKNEF GEERFLDSIH SSSLLNPEEQ ISKMQKDLNL 1740
FLQGAPIQDD FTLIAIEVF 1759 
Gene Ontology
 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0004672; F:protein kinase activity; IEA:InterPro. 
Interpro
 IPR003018; GAF.
 IPR011009; Kinase-like_dom.
 IPR027417; P-loop_NTPase.
 IPR001932; PP2C-like.
 IPR000719; Prot_kinase_cat_dom. 
Pfam
 PF01590; GAF
 PF00069; Pkinase
 PF07228; SpoIIE 
SMART
 SM00065; GAF
 SM00331; PP2C_SIG 
PROSITE
 PS50011; PROTEIN_KINASE_DOM 
PRINTS