CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-022684
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Vascular non-inflammatory molecule 3 
Protein Synonyms/Alias
 Vanin-3 
Gene Name
 Vnn3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
66DILESAIKLAARQGAubiquitination[1]
170TNVVFDSKGRLTARYubiquitination[1]
438LSGTFRTKYVFPQIVubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
 Amidohydrolase that hydrolyzes specifically one of the carboamide linkages in D-pantetheine thus recycling pantothenic acid (vitamin B5) and releasing cysteamine. 
Sequence Annotation
 DOMAIN 26 333 CN hydrolase.
 LIPID 469 469 GPI-anchor amidated glycine (Potential).
 CARBOHYD 39 39 N-linked (GlcNAc...) (Potential).
 CARBOHYD 147 147 N-linked (GlcNAc...) (Potential).
 CARBOHYD 270 270 N-linked (GlcNAc...) (Potential).
 CARBOHYD 319 319 N-linked (GlcNAc...) (Potential).
 CARBOHYD 357 357 N-linked (GlcNAc...) (Potential).  
Keyword
 Cell membrane; Complete proteome; Glycoprotein; GPI-anchor; Hydrolase; Lipoprotein; Membrane; Reference proteome; Signal. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 500 AA 
Protein Sequence
MASLHFPQWA VSFVFFAQAV GSMDTFIAAV YEHAVILPNK TESPVSTEEA LLLINKNIDI 60
LESAIKLAAR QGAHIIVTPE DGIYGWIFTR ETIYPYLEDI PDPEVNWIPC RDPRRFGYTP 120
VQERLSCLAK ENSIYIMANI GDKKPCNATD PHCPPDGRYQ YNTNVVFDSK GRLTARYHKY 180
NLFEPEIQFD FPKDSELVTF DTPFGKFGIF TCFDIFSYDP AVVVVKDTQV DSVLLPTAWY 240
NTLPLLSAVP FHSVWARAMG VNVLAANTHN TSMHMTGSGI YSPEAVRVYH YDMETESGQL 300
LLSELRSRPR QHATPAEVNW SAYARTVKPF SSGQADFPGK IYFDEFSFTK LTGSAGNYTV 360
CQKDLCCHLT YKMSESRMDE VYVLGAFDGL HTVEGQYYLQ ICTLLKCQTT NSRTCGEPVG 420
SAFTKFEEFS LSGTFRTKYV FPQIVLSGSQ LALERYYEVS RDGRLRSRGG APLPILVMAL 480
YGRVFERDPP RLGQGPGKLQ 500 
Gene Ontology
 GO:0031225; C:anchored to membrane; IEA:UniProtKB-KW.
 GO:0005615; C:extracellular space; IDA:BHF-UCL.
 GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
 GO:0017159; F:pantetheine hydrolase activity; IDA:BHF-UCL.
 GO:0015939; P:pantothenate metabolic process; IDA:BHF-UCL. 
Interpro
 IPR012101; Biotinidase_euk.
 IPR003010; C-N_Hydrolase. 
Pfam
 PF00795; CN_hydrolase 
SMART
  
PROSITE
 PS50263; CN_HYDROLASE 
PRINTS