CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-036063
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 General transcription factor IIH subunit 2 
Protein Synonyms/Alias
 General transcription factor IIH subunit 2-like protein; Uncharacterized protein 
Gene Name
 GTF2H2C 
Gene Synonyms/Alias
 GTF2H2 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
23ERTWEILKEDESGSLubiquitination[1, 2, 3, 4, 5]
31EDESGSLKATIEDILubiquitination[3]
40TIEDILFKAKRKRCAubiquitination[1, 2, 3, 5]
42EDILFKAKRKRCATFubiquitination[3, 5]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [3] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [4] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661]
 [5] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 51 AA 
Protein Sequence
MDEEPERTKR WEGGYERTWE ILKEDESGSL KATIEDILFK AKRKRCATFM W 51 
Gene Ontology
 GO:0000439; C:core TFIIH complex; IEA:InterPro.
 GO:0006289; P:nucleotide-excision repair; IEA:InterPro.
 GO:0006351; P:transcription, DNA-dependent; IEA:InterPro. 
Interpro
 IPR012170; TFIIH_SSL1/p44. 
Pfam
  
SMART
  
PROSITE
  
PRINTS