UniProt Accession

 CCNA_DROME; P14785; Q8IGR7; Q9VTP6; Q9VTP7 

Genbank Protein ID

 D10857; D10858; M24841; AE014296; AE014296; AY058712; BT001635 

Genbank Nucleotide ID

 BAA01628.1; BAA01629.1; AAA28435.1; AAF49999.2; AAF50000.3; AAL13941.1; AAN71390.1 

Protein Name

 G2/mitotic-specific cyclin-A 

Protein Synonyms/Alias

  

Gene Name

 CycA 

Gene Synonyms/Alias

 CG5940 

Created Date

 July 27, 2013 

Organism

 Drosophila melanogaster (Fruit fly) 

NCBI Taxa ID

 7227 

Lysine Modification

Position	Peptide	Type	References
37	PLAVIGGKAEKNALA	acetylation	[1]

Reference

 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702] 

Functional Description

 Essential for the control of the cell cycle at the G2/M (mitosis) transition. Interacts with the CDC2 and CDK2 protein kinases to form MPF. G2/M cyclins accumulate steadily during G2 and are abruptly destroyed at mitosis. 

Sequence Annotation

  

Keyword

 Alternative splicing; Cell cycle; Cell division; Complete proteome; Cyclin; Mitosis; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 491 AA 

Protein Sequence

Gene Ontology

 GO:0045169; C:fusome; TAS:FlyBase.
 GO:0005634; C:nucleus; IDA:UniProtKB.
 GO:0045170; C:spectrosome; IDA:FlyBase.
 GO:0016538; F:cyclin-dependent protein serine/threonine kinase regulator activity; NAS:UniProtKB.
 GO:0055059; P:asymmetric neuroblast division; IMP:FlyBase.
 GO:0046331; P:lateral inhibition; IMP:FlyBase.
 GO:0000070; P:mitotic sister chromatid segregation; IMP:FlyBase.
 GO:0007422; P:peripheral nervous system development; TAS:FlyBase.
 GO:0035561; P:regulation of chromatin binding; IGI:FlyBase.
 GO:0000079; P:regulation of cyclin-dependent protein serine/threonine kinase activity; IEA:InterPro.
 GO:0007096; P:regulation of exit from mitosis; IMP:FlyBase.
 GO:0010389; P:regulation of G2/M transition of mitotic cell cycle; IEA:InterPro.
 GO:0009794; P:regulation of mitotic cell cycle, embryonic; IMP:FlyBase.
 GO:0035186; P:syncytial blastoderm mitotic cell cycle; IGI:FlyBase. 

Interpro

 IPR013763; Cyclin-like.
 IPR015453; Cyclin_A.
 IPR014400; Cyclin_A/B/D/E.
 IPR004367; Cyclin_C-dom.
 IPR006671; Cyclin_N. 

Pfam

 PF02984; Cyclin_C
 PF00134; Cyclin_N 

SMART

 SM00385; CYCLIN 

PROSITE

 PS00292; CYCLINS 

PRINTS